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Found 10 of ic50 for drug = Acylanid
TargetSodium/potassium-transporting ATPase subunit alpha-1(Canis familiaris)
University Of Manitoba

Curated by ChEMBL
LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataIC50:  8nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 4C1(Homo sapiens)
Tohoku University

Curated by ChEMBL
LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataIC50:  120nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin uptake in OATP4C1-expressing MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Institut Pasteur Korea

LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataIC50:  230nMAssay Description:Ten-point DRCs were generated for each drug. Vero cells were seeded at 1.2 × 104 cells per well in DMEM, supplemented with 2% FBS and 1× ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3 [702-738,740-752](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataIC50:  700nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataIC50: >5.57E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetATP-binding cassette sub-family C member 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed