Affinity DataIC50: 0.00800nMAssay Description:Efficacy at muscarinic acetylcholine receptor M1 measured by the ability to inhibit the electrically stimulated twitch of the rabbit vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]OXO-M as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]-Pz as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-Pirenzepine (Pz) radioligand in rat hippocampus membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-pirenzepine (Pz) from rat hippocampus muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-oxotremorine-M (Oxo-M) as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]-pirenzepine in rat cerebral cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Displacement of [3H]-oxotremorine-M (Oxo-M) from rat hippocampus muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]-oxotremorine-M in rat brain membranesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
The University Of Toledo
Curated by ChEMBL
The University Of Toledo
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M2 expressed in A9 L cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:In vitro Muscarinic acetylcholine receptor M2 binding was evaluated in rat brain membranes by using [3H]- Oxo-MMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMpH: 6.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 6 in continuous presence of radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
The University Of Toledo
Curated by ChEMBL
The University Of Toledo
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M4 expressed in A9 L cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMpH: 8.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 8 in continuous presence of radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
The University Of Toledo
Curated by ChEMBL
The University Of Toledo
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Displacement of [3H]NMS from human muscarinic acetylcholine receptor M2 expressed in CHO cells after 60 mins by scintillation counting assayMore data for this Ligand-Target Pair
Affinity DataIC50: 955nMpH: 8.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 8 by wash-resistant binding methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMpH: 6.0Assay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells at pH 6 by wash-resistant binding methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by wash-resistant binding methodMore data for this Ligand-Target Pair