Affinity DataEC50: 3.60nMAssay Description:Agonist activity at human nociceptin opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 0.427nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as dynamic mass redistribution by DMR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 79nMAssay Description:Partial agonist activity at human KOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillatio...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0900nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding against human Opioid receptor like 1More data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:Effective concentration required to stimulate binding of GTPgammaS to Opioid receptor like 1 was determined using scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.389nMAssay Description:Antagonist activity at human recombinant NOP receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of N/OFQ-induced intracellu...More data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at human NOP receptor expressed in HEK293 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.230nMAssay Description:Agonist activity at human nociceptin receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production preincubated f...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist potency against GTPgammaS binding in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
Affinity DataEC50: 0.115nMAssay Description:Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)More data for this Ligand-Target Pair
Affinity DataEC50: 5.40nMAssay Description:Inhibition of electrically evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Inhibition of electrically evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataEC50: 8.10nMAssay Description:Partial agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillatio...More data for this Ligand-Target Pair