TargetAurora kinase A(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
US Patent
H. Lee Moffitt Cancer Center And Research Institute
US Patent
Affinity DataIC50: 2.80nM Kd: 17nMpH: 7.4Assay Description:The binding of inhibitors to Aurora A kinase was analyzed with a MicroCal iTC200 titration calorimeter (GE Healthcare, Piscataway, N.J.). The protein...More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Technical University Of Dortmund
Curated by ChEMBL
Technical University Of Dortmund
Curated by ChEMBL
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity to human acrylodan-labeled N-terminal His-tagged DDR2 (558 to 855 aa) by FLiK assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKd: 20nMAssay Description:Binding affinity to RIPK1 (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataKd: 6.5nMAssay Description:Binding affinity to non-auto-inhibited form of wild type human N-terminal GST-tagged FLT3 expressed in baculovirus expressionMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Heidelberg University
Curated by ChEMBL
Heidelberg University
Curated by ChEMBL
Affinity DataKd: 3.20nMAssay Description:Binding affinity to DNA-tagged human partial length TrkA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataKd: 14nMAssay Description:Binding affinity to human FLT3 D835H mutant expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Technische Universit£T Darmstadt
Curated by ChEMBL
Technische Universit£T Darmstadt
Curated by ChEMBL
Affinity DataKd: 45nMAssay Description:Binding affinity to human FLT3 ITD mutant expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Technical University Of Dortmund
Curated by ChEMBL
Technical University Of Dortmund
Curated by ChEMBL
Affinity DataKd: 230nMAssay Description:Binding affinity to wild type DDR2 (unknown origin) by FLiK assayMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
US Patent
H. Lee Moffitt Cancer Center And Research Institute
US Patent
Affinity DataKd: 0.501nMAssay Description:Binding affinity to DNA-tagged human partial length AURKA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair