Compile Data Set for Download or QSAR
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Found 20 of ki for monomerid = 50006774
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity to serotonin transporter (SERT) in rat forebrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  0.460nMAssay Description:Affinity for Serotonin transporter by displacing [3H]-Paroxetine from rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  0.460nMAssay Description:Ability to displace [3H]- paroxetine from Serotonin transporter in rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  0.480nMAssay Description:Binding affinity to dopamine transporter in membranes of cells selectively expressing the human genes for DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  0.480nMAssay Description:In vitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  0.670nMAssay Description:In vitro competitive binding versus [3H]-citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  0.960nMAssay Description:Displacement of [3H]-GBR-12,935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to dopamine transporter (DAT) in rat forebrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  1.30nMAssay Description:Ability to displace [3H]- beta-CIT from Dopamine transporter in rat striatal homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  1.40nMAssay Description:In vitro competitive binding versus [3H]- nisoxatine in murine kidney cells transfected with cDNA for human norepinephrine transporter (NET)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to norepinephrine (NE) transporter in rat forebrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  2.80nMAssay Description:Ability to displace [3H]- nisoxetin from Norepinephrine transporter in rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  2.80nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]-Nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]- paroxetine from serotonin transporter (5-HTT) in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  11nMAssay Description:Binding affinity to norepinephrine (NE) transporter in membranes of cells selectively expressing the human genes for NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]GBR-12935 from dopamine transporter (DAT) in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Yale School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50006774((2S,3S)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporter (NET) in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed