TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to opioid receptors by the displacement of [3H]fentanyl in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Displacement [3H]naloxone from rat-brain Opioid receptorsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig ileum/longitudinal muscle with myenteric plexus assessed as inhibition of PL-017-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Compound was tested in vitro for binding affinity towards mu opioid receptor by measuring displacement of [3H]-DAGO from guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:In vitro binding activity against opioid receptor mu using [3H]-DAGO as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 3.45nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Agonist activity at delta opioid receptor in beta-funaltrexamine-treated mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Agonist activity at Gi-coupled mu opioid receptor (unknown origin) expressed in HEK293T cells assessed as inhibition of cAMP production at pH 6.5 mea...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Agonist activity at delta opioid receptor in ICR mouse vas deferens assessed as inhibition of MVD contraction heightMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibition of delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 9.45nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Agonist activity at mu opioid receptor in beta-funaltrexamine-treated guinea pig isolated ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Agonist activity at Gi-coupled mu opioid receptor (unknown origin) expressed in HEK293T cells assessed as inhibition of cAMP production at pH 7.4 mea...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]nalotrexone from rat-brain Opioid receptorsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:In vivo binding affinity to opioid receptor preparations from rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 187nMAssay Description:Compound was tested in vitro for binding affinity towards delta opioid receptor by measuring displacement of [3H]-DPDPE from guinea pig brain membran...More data for this Ligand-Target Pair
Affinity DataIC50: 187nMAssay Description:In vitro binding activity against opioid receptor delta using [3DPDPE] as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 431nMAssay Description:Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of [3H] DAMGO from rat mu-opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reverse Proteomics Research Institute
Curated by ChEMBL
Reverse Proteomics Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Agonist activity at mu opioid receptor in guinea pig isolated ileum assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 5.89E+3nMAssay Description:In vitro binding activity against opioid receptor kappa using [3H]-EKC as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 5.89E+3nMAssay Description:Compound was tested in vitro for binding affinity towards kappa opioid receptor by measuring displacement of [3H]-EKC from guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+3nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in Sprague-Dawley rat brain membrane after 2 hr by scintillation countingMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 1(Homo sapiens (Human))
University Medicine Greifswald
Curated by ChEMBL
University Medicine Greifswald
Curated by ChEMBL
Affinity DataIC50: 4.62E+4nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as reduction in ASP+ substrate uptake by microplate reader based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+5nMAssay Description:Antagonist activity at H1 receptor in human HeLa cells assessed as inhibition of histamine-induced Ca2+ release by using fura-2AM-based fluorescence ...More data for this Ligand-Target Pair