TargetMajor prion protein(Mus musculus)
Scuola Internazionale Superiore Di Studi Avanzati (Sissa)
Curated by ChEMBL
Scuola Internazionale Superiore Di Studi Avanzati (Sissa)
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Synergistic anti-prion activity of mouse ScN2a cells infected with RML prion assessed as reduction of RML accumulation by isobologram analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Jagiellonian University
Curated by ChEMBL
Jagiellonian University
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in rat ventricular myocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of cGAS (unknown origin) incubated for 1 hr by Typhoon imaging system analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of cGAS in human THP-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rabbit aldehyde oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of recombinant His-tagged Leishmania infantum TryR oxidoreductase activity expressed in Escherichia coli BL21 (DE3) using TS2 and NADPH as...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Southern Research Institute
Curated by PubChem BioAssay
Southern Research Institute
Curated by PubChem BioAssay
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Escherichia coli DNA-primed RNA polymerase activity using [8-14C]ATP by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.26E+4nMAssay Description:Tested for its inhibitory activity against PGS (prostaglandin synthetase).More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Ten-point DRCs were generated for each drug. Vero cells were seeded at 1.2 × 104 cells per well in DMEM, supplemented with 2% FBS and 1× ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for its inhibitory activity against Phospholipase A2 (PLA2)More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human placental Monoamine oxidase A (competitive inhibition was observed)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+5nMAssay Description:Tested for its inhibitory activity against 5-lipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibitory concentration of the compound against trypanothione reductase was determinedMore data for this Ligand-Target Pair
TargetHistidine-rich protein PFHRP-II(Plasmodium falciparum)
Kyoto Institute Of Technology
Curated by ChEMBL
Kyoto Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.92E+5nMAssay Description:Inhibition of Tween 20-induced beta-hematin formation by colorimetric assayMore data for this Ligand-Target Pair
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration of the compound against human Glutathione reductase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+6nMAssay Description:Inhibition of Naja Naja PLA2More data for this Ligand-Target Pair
Affinity DataIC50: 2.16E+6nMAssay Description:Inhibition of snake venom phospholipase A2 assessed as oxygen consumption for 3 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+7nMAssay Description:In vitro inhibition of human recombinant secretory Phospholipase A2 (group II).More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+8nMAssay Description:In vitro inhibition of rat secretory Phospholipase A2 (group II).More data for this Ligand-Target Pair