Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ic50 for monomerid = 50017233
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataIC50:  0.00400nMAssay Description:50% Inhibition of stereospecific [3H]-naltrexone (10e-9 M) binding towards opiate receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataIC50:  0.130nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(GUINEA PIG)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataIC50:  0.600nMAssay Description:Inhibitory activity against opioid receptor mu of guinea pig brain using [3H]DAGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity against opioid receptor delta of guinea pig was determined by using [3H]DADLE radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataIC50:  4nMAssay Description:In vitro binding affinity against cloned human Opioid receptor kappa 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataIC50:  5.10nMAssay Description:In vitro binding affinity against cloned human Opioid receptor delta 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(GUINEA PIG)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataIC50:  17nMAssay Description:Inhibitory potency against Opioid receptor mu 1 in the guinea pig ileum assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataIC50:  278nMAssay Description:Inhibitory potency against Opioid receptor mu 1 in mouse vas deferens assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataIC50:  4.00E+3nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 1(Homo sapiens (Human))
University Medicine Greifswald

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as reduction in ASP+ substrate uptake by microplate reader based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed