TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.00400nMAssay Description:50% Inhibition of stereospecific [3H]-naltrexone (10e-9 M) binding towards opiate receptor in rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against opioid receptor mu of guinea pig brain using [3H]DAGO radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibitory activity against opioid receptor delta of guinea pig was determined by using [3H]DADLE radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro binding affinity against cloned human Opioid receptor kappa 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:In vitro binding affinity against cloned human Opioid receptor delta 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory potency against Opioid receptor mu 1 in the guinea pig ileum assayMore data for this Ligand-Target Pair
Affinity DataIC50: 278nMAssay Description:Inhibitory potency against Opioid receptor mu 1 in mouse vas deferens assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration required to inhibit [3H]naltrexone binding to Opioid receptorsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 1(Homo sapiens (Human))
University Medicine Greifswald
Curated by ChEMBL
University Medicine Greifswald
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as reduction in ASP+ substrate uptake by microplate reader based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair