Affinity DataIC50: 7.70nMAssay Description:Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranesMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck
Curated by ChEMBL
H. Lundbeck
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Binding affinity against dopamine receptor D2 More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Binding affinity against dopamine receptor D2 More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair