Compile Data Set for Download or QSAR
maximum 50k data
Found 16 of ec50 for monomerid = 50022721
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  920nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  786nMAssay Description:Activation of mouse wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  280nMAssay Description:Activation of rat TAAR1 expressed in HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  210nMAssay Description:Activation of rat TAAR1 expressed in HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  1.40E+3nMAssay Description:Activation of rat TAAR1 expressed in Syrian hamster AV12-664 cells assessed as accumulation of cAMP after 30 mins using cAMP XS EA/CL as substrate by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  4.96E+3nMAssay Description:Activation of mouse TAAR1 expressed in human HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  65nMAssay Description:Activation of mouse TAAR1 expressed in human HEK293 cells assessed as accumulation of cAMP after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  1.70E+3nMAssay Description:Activation of human TAAR1 expressed in Syrian hamster AV12-664 cells co-expressing GalphaS protein assessed as accumulation of cAMP after 30 mins usi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  250nMAssay Description:Activation of human TAAR1 expressed in human HEK293T cells assessed as cAMP accumulation after 10 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Macaca mulatta)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  1.86E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  170nMAssay Description:Activation of rat TAAR1 transmembrane domain 7 Asn287(7.39)Tyr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  214nMAssay Description:Activation of rat TAAR1 transmembrane domain 6 Met268(6.55)Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  121nMAssay Description:Activation of mouse TAAR1 transmembrane domain 6 Thr268(6.55)Met mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  34nMAssay Description:Activation of rat wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  105nMAssay Description:Activation of mouse TAAR1 transmembrane domain 7 Tyr287(7.39)Asn mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | AMPHETAMINE | CHEMBL19393)
Affinity DataEC50:  1.30E+3nMAssay Description:Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed