TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Technology Sydney
Curated by ChEMBL
University Of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 8.89E+3nMAssay Description:Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity at 5 uM active compound by Lineweaver-Burk plot analy...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](Agaricus bisporus (Mushroom))
University Of Technology Sydney
University Of Technology Sydney
Affinity DataKi: 1.22E+4nM IC50: 2.75E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Technology Sydney
Curated by ChEMBL
University Of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 1.22E+4nMAssay Description:Competitive inhibition of mushroom tyrosinase polyphenol oxidase activity using L-DOPA as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Technology Sydney
Curated by ChEMBL
University Of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 1.49E+4nMAssay Description:Competitive inhibition of mushroom tyrosinase diphenolase activity assessed as L-DOPA conversion to dopachrome by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Technology Sydney
Curated by ChEMBL
University Of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activityMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+4nMAssay Description:Competitive inhibition of pig kidney DAAO using D-Alanine as substrate by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Technology Sydney
Curated by ChEMBL
University Of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 2.23E+4nMAssay Description:Inhibition of mashroom tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Technology Sydney
Curated by ChEMBL
University Of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 3.00E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as inhibition constant for compound-free enzyme using as L-tyrosine substrate by spectrophotometric analys...More data for this Ligand-Target Pair
Affinity DataKi: 3.50E+5nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Technology Sydney
Curated by ChEMBL
University Of Technology Sydney
Curated by ChEMBL
Affinity DataKi: 5.83E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as oxidation of L-DOPAMore data for this Ligand-Target Pair
Affinity DataKi: 5.50E+6nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 120 uM by Lineweaver-Burk plotMore data for this Ligand-Target Pair