Affinity DataIC50: 2.00E+3nMAssay Description:DNTB-Coupled_Enzyme_AssayMore data for this Ligand-Target Pair
TargetPolymerase acidic protein(Influenza A virus (strain A/X-31 H3N2))
Polo Universitario Ss. Annunziata
Curated by ChEMBL
Polo Universitario Ss. Annunziata
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant Influenza A virus (A/X-31(H3N2)) N-terminal 6xHis-tagged PA-Nter (1 to 217 residues) expressed in Escherichia coli BL21-Cod...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibitory activity against Hepatitis C virus RNA dependent RNA polymerase nonstructural protein 5BMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibitory concentration against hepatitis C virus polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B of hepatitis C virusMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B is determinedMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Max Planck Institute Of Molecular Physiology
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of cap 1 ALMV primed Influenza transcriptaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza virus RNPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assay in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+4nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.49E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Concentration required to inhibit strand transfer of HIV-1 integrase using Mn2+ as a divalent cation source.More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Integrase catalyzed strand transfer (ST) as measured in an in vitro assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assay in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibitory activity of the compound against HIV-1 reverse transcriptase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+4nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of exogenous cobalt ionMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of HIV1 integrase 3' processing activity in presence of exogenous cobalt ionMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory effect on 3'-processing(3'-P) of proviral DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.33E+5nMAssay Description:Inhibition of HIV1 integrase 3' processing activityMore data for this Ligand-Target Pair