Compile Data Set for Download or QSAR
maximum 50k data
Found 65 of ic50 for monomerid = 50235830
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  8nMAssay Description:Inhibition of Syk (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  17nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  46nMAssay Description:Inhibition of PAK4 kinase domain (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  57nMAssay Description:Inhibition of JAK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  82nMAssay Description:Inhibition of JNK1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  83nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  115nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  126nMAssay Description:Inhibition of TrkB (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  132nMAssay Description:Inhibition of RET (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  136nMAssay Description:Inhibition of FAK (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  139nMAssay Description:Inhibition of MEK1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor-like protein(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  177nMAssay Description:Inhibition of MST1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  211nMAssay Description:Inhibition of CLK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  248nMAssay Description:Inhibition of ROCK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  266nMAssay Description:Inhibition of ALK (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukocyte tyrosine kinase receptor(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  360nMAssay Description:Inhibition of LTK (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  391nMAssay Description:Inhibition of MEK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  413nMAssay Description:Inhibition of ROCK1(unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  433nMAssay Description:Inhibition of JNK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  472nMAssay Description:Inhibition of AURKA (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  496nMAssay Description:Inhibition of JAK3 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  502nMAssay Description:Inhibition of INSR (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TAO2(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  529nMAssay Description:Inhibition of TAOK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  558nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  606nMAssay Description:Inhibition of SGK1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  872nMAssay Description:Inhibition of CK1alpha1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  886nMAssay Description:Inhibition of KDR (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  892nMAssay Description:Inhibition of MAP4K4 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  991nMAssay Description:Inhibition of TTK (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of TBK1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of ABL (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D3(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of Prkcn (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of AURKB (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of DYRK1B (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of TrkC (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of ZIPK (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of IKKE (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  2.33E+3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  2.48E+3nMAssay Description:Inhibition of human CAMK1D (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibition of CDK7 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  2.94E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  3.51E+3nMAssay Description:Inhibition of TRKA (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  3.65E+3nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  4.06E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  4.22E+3nMAssay Description:Inhibition of Flt1(unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  4.31E+3nMAssay Description:Inhibition of PDGFRA (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50235830(CHEMBL2006765)
Affinity DataIC50:  4.95E+3nMAssay Description:Inhibition of GRK5 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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