Found 9 of ic50 for drug = Akrinol TargetTyrosinase(Homo sapiens (Human))
Tokyo University Of Agriculture And Technology
Curated by ChEMBL
Tokyo University Of Agriculture And Technology
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Tokyo University Of Agriculture And Technology
Curated by ChEMBL
Tokyo University Of Agriculture And Technology
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Tokyo University Of Agriculture And Technology
Curated by ChEMBL
Tokyo University Of Agriculture And Technology
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of mushroom tyrosinase using TBC as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Tokyo University Of Agriculture And Technology
Curated by ChEMBL
Tokyo University Of Agriculture And Technology
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibition of mushroom tyrosine kinase assessed as oxidation of 0.25 mM L-3,4-dihydroxyphenylalanineMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno
Curated by ChEMBL
University Of Salerno
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of 5-LO in human PMNL using arachidonic acid as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno
Curated by ChEMBL
University Of Salerno
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate after 10 minsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Salerno
Curated by ChEMBL
University Of Salerno
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 15-LO in human PMNL using arachidonic acid as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University Of Salerno
Curated by ChEMBL
University Of Salerno
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 12-LO in human PMNL using arachidonic acid preincubated for 15 minsMore data for this Ligand-Target Pair
TargetTyrosinase(Homo sapiens (Human))
Tokyo University Of Agriculture And Technology
Curated by ChEMBL
Tokyo University Of Agriculture And Technology
Curated by ChEMBL
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
