Compile Data Set for Download or QSAR
maximum 50k data
Found 47 of ki for monomerid = 50449038
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  66nMpH: 7.4Assay Description:To test for enzyme inhibition, the hemoglobin capture assay was used to measure nitric oxide production. The assay was performed at 37° C. in HEPES b...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  66nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured for ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  66nMAssay Description:Inhibition of wild type recombinant rat nNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  66nMAssay Description:Inhibition of recombinant rat nNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  66nMAssay Description:Inhibition of recombinant rat nNOS expressed in Escherichia coli assessed as reduction in nitric oxide production using L-arginine as substrate measu...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  66nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli using L-arginine as substrate assessed as NO production by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]Way100635 from human 5-HT1A receptor expressed in CHO cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]Tiotidine from human H2 receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]5-HT from human 5-HT1E receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2C receptor expressed in Flp-IN HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]LSD from human 5-HT5A receptor expressed in Flp-In CHO cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]Cimetidine from human H2 receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]Way100635 from human 5-HT1a receptor expressed in CHO cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]LSD from human 5-HT7A receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]Pyrilamine from human H1 receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]N/OFQ from human nociceptin opioid receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]alpha-methylhistamine from human H3 receptor expressed in HEK Flp-In cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]Histamine from human H4 receptor after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]5-CT from human 5-HT1B receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]5-CT from human 5-HT1D receptor expressed in HEKT cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4 receptor after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]GR65630 from human 5-HT3 receptor expressed in HEKT cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Displacement of [3H]Ketanserin from human 5-HT2A receptor expressed in HEKT cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi: <100nMAssay Description:Binding affinity to human 5-HT1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  440nMAssay Description:Inhibition of recombinant human nNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  440nMAssay Description:Inhibition of recombinant human full-length nNOS expressed in Escherichia coli BL21(DE3) assessed as reduction in nitric oxide production using L-arg...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  440nMAssay Description:Inhibition of recombinant human nNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  440nMpH: 7.4Assay Description:To test for enzyme inhibition, the hemoglobin capture assay was used to measure nitric oxide production. The assay was performed at 37° C. in HEPES b...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  440nMAssay Description:Inhibition of human nNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured fo...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  7.24E+3nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  7.24E+3nMpH: 7.4Assay Description:To test for enzyme inhibition, the hemoglobin capture assay was used to measure nitric oxide production. The assay was performed at 37° C. in HEPES b...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  7.24E+3nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli using L-arginine as substrate assessed as NO production by hemoglobin capture ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  7.24E+3nMAssay Description:Inhibition of recombinant bovine eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  1.18E+4nMAssay Description:Inhibition of recombinant human full-length eNOS expressed in Escherichia coli BL21(DE3) assessed as reduction in nitric oxide production using L-arg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  1.18E+4nMAssay Description:Inhibition of human eNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  1.18E+4nMAssay Description:Inhibition of recombinant human eNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  2.84E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli using L-arginine as substrate assessed as NO production by hemoglobin capture assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  2.84E+4nMpH: 7.4Assay Description:To test for enzyme inhibition, the hemoglobin capture assay was used to measure nitric oxide production. The assay was performed at 37° C. in HEPES b...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  2.84E+4nMAssay Description:Inhibition of recombinant mouse macrophage iNOS expressed in Escherichia coli assessed as reduction in nitric oxide production using L-arginine as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  2.84E+4nMAssay Description:Inhibition of recombinant murine iNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  2.84E+4nMAssay Description:Inhibition of mouse iNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50449038(CHEMBL3126204 | US9212144, 15 (Ex. 17))
Affinity DataKi:  2.84E+4nMAssay Description:Inhibition of recombinant mouse macrophage iNOS expressed in Escherichia coli using L-arginine as substrate after 30 secs by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed