Affinity DataKi: 64nMAssay Description:Inhibition of CYP1B1 EROD activity assessed as inhibition of deethylation of 7-ethoxyresorufin to resorufinMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Inhibition of CYP1A1 EROD activity assessed as inhibition of deethylation of 7-ethoxyresorufin to resorufinMore data for this Ligand-Target Pair
Affinity DataKi: 520nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 740nM ΔG°: -8.27kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Inhibition of CK2alpha (unknown origin)More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
The Hong Kong Polytechnic University
Curated by ChEMBL
The Hong Kong Polytechnic University
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of MRP1 transfected in human HeLa cells assessed as inhibition of [3H]LTC4 transport by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Displacement of specific [3H]-PIA binding from adenosine A1 receptor in rat brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 3.02E+3nMAssay Description:Ability to displace [3H]N6-phenylisopropyladenosine binding from adenosine A1 receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 4.10E+3nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
The Hong Kong Polytechnic University
Curated by ChEMBL
The Hong Kong Polytechnic University
Curated by ChEMBL
Affinity DataKi: 4.90E+3nMAssay Description:TP_TRANSPORTER: inhibition of LTC4 uptake (+3mM GSH) in membrane vesicle from MRP1-expressing HeLa cellsMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
University Of Hradec Kralove
Curated by ChEMBL
University Of Hradec Kralove
Curated by ChEMBL
Affinity DataKi: 6.00E+3nMAssay Description:Non-competitive inhibition of recombinant human N-terminal His6-tagged AKR1B10 expressed in Escherichia coli BL21 cells using all-trans-retinal as su...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataKi: 7.58E+3nMAssay Description:Affinity at Adenosine A2A receptor in rat striatal membranes by [3H]- CGS 21680 displacement.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataKi: 7.59E+3nMAssay Description:Ability to displace [3H]-CGS- 21680 binding from adenosine A2A receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 9.10E+3nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
Affinity DataKi: 1.13E+4nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.16E+4nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
Affinity DataKi: 3.10E+4nMAssay Description:Competitive inhibition of Helicobacter pylori Ddl using ATP as substrateMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Affinity DataKi: 3.74E+4nMAssay Description:Inhibition of human plasma BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataKi: 4.99E+4nMAssay Description:Noncompetitive inhibition of human neutrophil elastase using varying levels of MeOSuc-AAPV-pNA as substrate measured after 30 mins by double-reciproc...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Punjabi University
Curated by ChEMBL
Punjabi University
Curated by ChEMBL
Affinity DataKi: 8.10E+4nMAssay Description:Inhibition of forskolin-stimulated CFTR (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Institute For Medical Research And Occupational Health
Curated by ChEMBL
Affinity DataKi: 1.22E+5nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Universidade Do Porto
Curated by ChEMBL
Universidade Do Porto
Curated by ChEMBL
Affinity DataKi: 1.78E+5nMAssay Description:Mixed noncompetitive type inhibition of soybean LOX-1 using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by Line...More data for this Ligand-Target Pair