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Compile Data Set for Download or QSAR

Found 57 hits of affinity data for UniProtKB/TrEMBL: Q7L5A8   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty acid 2-hydroxylase


(Human)
BDBM483644
PNG
(US10927105, Ex 17)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CC2CN(Cc3ccc(cc3C(F)(F)F)N3CCOCC3)CC2C1
Show InChI InChI=1S/C23H27F3N6O3/c24-23(25,26)19-9-18(30-5-7-35-8-6-30)2-1-15(19)10-29-11-16-13-31(14-17(16)12-29)22(34)32-4-3-20(28-32)21(27)33/h1-4,9,16-17H,5-8,10-14H2,(H2,27,33)
MMDB

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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483723
PNG
(1-(5-(3- (trifluoromethyl)- benzyl)- octahydropyrr...)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CC2CN(Cc3cccc(c3)C(F)(F)F)CC2C1
Show InChI InChI=1S/C19H20F3N5O2/c20-19(21,22)15-3-1-2-12(6-15)7-25-8-13-10-26(11-14(13)9-25)18(29)27-5-4-16(24-27)17(23)28/h1-6,13-14H,7-11H2,(H2,23,28)
MMDB

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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483722
PNG
(1-(cis-5-((2- chlorobenzyl)- (methyl)amino)- octah...)
Show SMILES CN(Cc1ccccc1Cl)[C@H]1C[C@H]2CN(C[C@H]2C1)C(=O)n1ccc(n1)C(N)=O
Show InChI InChI=1S/C20H24ClN5O2/c1-24(10-13-4-2-3-5-17(13)21)16-8-14-11-25(12-15(14)9-16)20(28)26-7-6-18(23-26)19(22)27/h2-7,14-16H,8-12H2,1H3,(H2,22,27)/t14-,15+,16-
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483721
PNG
(1-(cis-5-(methyl(4- (trifluoromethyl)- benzyl)amin...)
Show SMILES CN(Cc1ccc(cc1)C(F)(F)F)[C@H]1C[C@H]2CN(C[C@H]2C1)C(=O)n1ccc(n1)C(N)=O
Show InChI InChI=1S/C21H24F3N5O2/c1-27(10-13-2-4-16(5-3-13)21(22,23)24)17-8-14-11-28(12-15(14)9-17)20(31)29-7-6-18(26-29)19(25)30/h2-7,14-15,17H,8-12H2,1H3,(H2,25,30)/t14-,15+,17-
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483720
PNG
(1-(cis-5-(methyl(2- (trifluoromethyl)- benzyl)amin...)
Show SMILES CN(Cc1ccccc1C(F)(F)F)[C@H]1C[C@H]2CN(C[C@H]2C1)C(=O)n1ccc(n1)C(N)=O
Show InChI InChI=1S/C21H24F3N5O2/c1-27(10-13-4-2-3-5-17(13)21(22,23)24)16-8-14-11-28(12-15(14)9-16)20(31)29-7-6-18(26-29)19(25)30/h2-7,14-16H,8-12H2,1H3,(H2,25,30)/t14-,15+,16-
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483719
PNG
(1-(5-(2,5- dichlorobenzyl)- octahydropyrrolo- [3,4...)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CC2CN(Cc3cc(Cl)ccc3Cl)CC2C1
Show InChI InChI=1S/C18H19Cl2N5O2/c19-14-1-2-15(20)11(5-14)6-23-7-12-9-24(10-13(12)8-23)18(27)25-4-3-16(22-25)17(21)26/h1-5,12-13H,6-10H2,(H2,21,26)
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483718
PNG
(1-(5-(3-chloro-5- (trifluoromethyl)- benzyl)- octa...)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CC2CN(Cc3cc(Cl)cc(c3)C(F)(F)F)CC2C1
Show InChI InChI=1S/C19H19ClF3N5O2/c20-15-4-11(3-14(5-15)19(21,22)23)6-26-7-12-9-27(10-13(12)8-26)18(30)28-2-1-16(25-28)17(24)29/h1-5,12-13H,6-10H2,(H2,24,29)
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483717
PNG
(1-(trans-5-((2- chlorobenzyl)- (methyl)amino)- oct...)
Show SMILES CN(Cc1ccccc1Cl)[C@@H]1C[C@H]2CN(C[C@H]2C1)C(=O)n1ccc(n1)C(N)=O
Show InChI InChI=1S/C20H24ClN5O2/c1-24(10-13-4-2-3-5-17(13)21)16-8-14-11-25(12-15(14)9-16)20(28)26-7-6-18(23-26)19(22)27/h2-7,14-16H,8-12H2,1H3,(H2,22,27)/t14-,15+,16+
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483714
PNG
(1-(2-(3-chloro-5- (trifluoromethyl)- benzyl)-2,8- ...)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CCC2(CCN(Cc3cc(Cl)cc(c3)C(F)(F)F)C2)CC1
Show InChI InChI=1S/C21H23ClF3N5O2/c22-16-10-14(9-15(11-16)21(23,24)25)12-28-6-2-20(13-28)3-7-29(8-4-20)19(32)30-5-1-17(27-30)18(26)31/h1,5,9-11H,2-4,6-8,12-13H2,(H2,26,31)
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483713
PNG
(1-(2-(4-(pyrrolidin- 1-yl)-2- (trifluoromethyl)- b...)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CCC2(CCN(Cc3ccc(cc3C(F)(F)F)N3CCCC3)C2)CC1
Show InChI InChI=1S/C25H31F3N6O2/c26-25(27,28)20-15-19(32-9-1-2-10-32)4-3-18(20)16-31-12-6-24(17-31)7-13-33(14-8-24)23(36)34-11-5-21(30-34)22(29)35/h3-5,11,15H,1-2,6-10,12-14,16-17H2,(H2,29,35)
MMDB

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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483712
PNG
(1-(4-(methyl(3- (trifluoromethyl)- benzyl)amino)- ...)
Show SMILES CN(Cc1cccc(c1)C(F)(F)F)C1CCN(CC1)C(=O)n1ccc(n1)C(N)=O
Show InChI InChI=1S/C19H22F3N5O2/c1-25(12-13-3-2-4-14(11-13)19(20,21)22)15-5-8-26(9-6-15)18(29)27-10-7-16(24-27)17(23)28/h2-4,7,10-11,15H,5-6,8-9,12H2,1H3,(H2,23,28)
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483710
PNG
(1-(4-(2-(pyrrolidin- 1-yl)-4- (trifluoromethyl)- b...)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CCN(Cc2ccc(cc2N2CCCC2)C(F)(F)F)CC1
Show InChI InChI=1S/C21H25F3N6O2/c22-21(23,24)16-4-3-15(18(13-16)28-6-1-2-7-28)14-27-9-11-29(12-10-27)20(32)30-8-5-17(26-30)19(25)31/h3-5,8,13H,1-2,6-7,9-12,14H2,(H2,25,31)
MMDB

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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483709
PNG
(1-(trans-5-((3- methyl-4- (trifluoromethyl)- benyl...)
Show SMILES Cc1cc(CO[C@@H]2C[C@H]3CN(C[C@H]3C2)C(=O)n2ccc(n2)C(O)=O)ccc1C(F)(F)F
Show InChI InChI=1S/C21H22F3N3O4/c1-12-6-13(2-3-17(12)21(22,23)24)11-31-16-7-14-9-26(10-15(14)8-16)20(30)27-5-4-18(25-27)19(28)29/h2-6,14-16H,7-11H2,1H3,(H,28,29)/t14-,15+,16+
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483703
PNG
(1-(4-(3-(4- chlorophenoxy)-5- fluorobenzyl)- piper...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1CCN(Cc2cc(F)cc(Oc3ccc(Cl)cc3)c2)CC1
Show InChI InChI=1S/C22H20ClFN4O4/c23-16-1-3-18(4-2-16)32-19-12-15(11-17(24)13-19)14-26-7-9-27(10-8-26)22(31)28-6-5-20(25-28)21(29)30/h1-6,11-13H,7-10,14H2,(H,29,30)
MMDB

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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483701
PNG
(1-(trans-5-((3-(4- chlorophenoxy)- benzyl)oxy)- oc...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1C[C@@H]2C[C@H](C[C@@H]2C1)OCc1cccc(Oc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C25H24ClN3O5/c26-19-4-6-20(7-5-19)34-21-3-1-2-16(10-21)15-33-22-11-17-13-28(14-18(17)12-22)25(32)29-9-8-23(27-29)24(30)31/h1-10,17-18,22H,11-15H2,(H,30,31)/t17-,18+,22+
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483696
PNG
(1-(4-(4- ethynylbenzyl)- piperazine-1- carbonyl)- ...)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CCN(Cc2ccc(cc2)C#C)CC1
Show InChI InChI=1S/C18H19N5O2/c1-2-14-3-5-15(6-4-14)13-21-9-11-22(12-10-21)18(25)23-8-7-16(20-23)17(19)24/h1,3-8H,9-13H2,(H2,19,24)
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483693
PNG
(4-chloro-1-(1-((6- (trifluoromethyl)- benzo[b]thio...)
Show SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CCC2(CCCN2Cc2cc3ccc(cc3s2)C(F)(F)F)CC1
Show InChI InChI=1S/C23H22ClF3N4O3S/c24-17-13-31(28-19(17)20(32)33)21(34)29-8-5-22(6-9-29)4-1-7-30(22)12-16-10-14-2-3-15(23(25,26)27)11-18(14)35-16/h2-3,10-11,13H,1,4-9,12H2,(H,32,33)
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483687
PNG
(4-chloro-1-(4-(3-(4- chlorophenoxy)- benzyl)- pipe...)
Show SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1
Show InChI InChI=1S/C22H20Cl2N4O4/c23-16-4-6-17(7-5-16)32-18-3-1-2-15(12-18)13-26-8-10-27(11-9-26)22(31)28-14-19(24)20(25-28)21(29)30/h1-7,12,14H,8-11,13H2,(H,29,30)
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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483683
PNG
(4-chloro-1-(trans-5- ((2-chlorobenzyl)- (methyl)am...)
Show SMILES CN(Cc1ccccc1Cl)[C@@H]1C[C@H]2CN(C[C@H]2C1)C(=O)n1cc(Cl)c(n1)C(N)=O
Show InChI InChI=1S/C20H23Cl2N5O2/c1-25(8-12-4-2-3-5-16(12)21)15-6-13-9-26(10-14(13)7-15)20(29)27-11-17(22)18(24-27)19(23)28/h2-5,11,13-15H,6-10H2,1H3,(H2,23,28)/t13-,14+,15+
MMDB

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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483682
PNG
(1-(trans-5-([1,1'- biphenyl]-3- yloxy)- octahydroc...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1C[C@@H]2C[C@H](C[C@@H]2C1)Oc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C24H23N3O4/c28-23(29)22-9-10-27(25-22)24(30)26-14-18-12-21(13-19(18)15-26)31-20-8-4-7-17(11-20)16-5-2-1-3-6-16/h1-11,18-19,21H,12-15H2,(H,28,29)/t18-,19+,21+
MMDB

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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483677
PNG
(1-(2-(5-chloro-2- (trifluoromethyl)- benzyl)-2,8- ...)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CCC2(CCN(Cc3cc(Cl)ccc3C(F)(F)F)C2)CC1
Show InChI InChI=1S/C21H23ClF3N5O2/c22-15-1-2-16(21(23,24)25)14(11-15)12-28-8-4-20(13-28)5-9-29(10-6-20)19(32)30-7-3-17(27-30)18(26)31/h1-3,7,11H,4-6,8-10,12-13H2,(H2,26,31)
MMDB

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n/an/a<100n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483664
PNG
(1-(trans-5-((4-(4- chlorophenoxy)- benzyl)oxy)- oc...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1C[C@@H]2C[C@H](C[C@@H]2C1)OCc1ccc(Oc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C25H24ClN3O5/c26-19-3-7-21(8-4-19)34-20-5-1-16(2-6-20)15-33-22-11-17-13-28(14-18(17)12-22)25(32)29-10-9-23(27-29)24(30)31/h1-10,17-18,22H,11-15H2,(H,30,31)/t17-,18+,22+
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483685
PNG
(1-(2-(5-chloro-2- (trifluoromethyl)- benzyl)-2,8- ...)
Show SMILES Cc1cn(nc1C(O)=O)C(=O)N1CCC2(CCN(Cc3cc(Cl)ccc3C(F)(F)F)C2)CC1
Show InChI InChI=1S/C22H24ClF3N4O3/c1-14-11-30(27-18(14)19(31)32)20(33)29-8-5-21(6-9-29)4-7-28(13-21)12-15-10-16(23)2-3-17(15)22(24,25)26/h2-3,10-11H,4-9,12-13H2,1H3,(H,31,32)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483642
PNG
(US10927105, Ex 15)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1C[C@@H]2C[C@H](C[C@@H]2C1)OCc1ccccc1Cl
Show InChI InChI=1S/C19H20ClN3O4/c20-16-4-2-1-3-12(16)11-27-15-7-13-9-22(10-14(13)8-15)19(26)23-6-5-17(21-23)18(24)25/h1-6,13-15H,7-11H2,(H,24,25)/t13-,14+,15+
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483688
PNG
(4-chloro-1-(2-(5- chloro-2- (trifluoromethyl)- ben...)
Show SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CCC2(CCN(Cc3cc(Cl)ccc3C(F)(F)F)C2)CC1
Show InChI InChI=1S/C21H21Cl2F3N4O3/c22-14-1-2-15(21(24,25)26)13(9-14)10-28-6-3-20(12-28)4-7-29(8-5-20)19(33)30-11-16(23)17(27-30)18(31)32/h1-2,9,11H,3-8,10,12H2,(H,31,32)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483689
PNG
(4-chloro-1-(2-(5- chloro-2- (trifluoromethyl)- ben...)
Show SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CCC2(CN(Cc3cc(Cl)ccc3C(F)(F)F)C2)CC1
Show InChI InChI=1S/C20H19Cl2F3N4O3/c21-13-1-2-14(20(23,24)25)12(7-13)8-27-10-19(11-27)3-5-28(6-4-19)18(32)29-9-15(22)16(26-29)17(30)31/h1-2,7,9H,3-6,8,10-11H2,(H,30,31)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483690
PNG
(4-chloro-1-(5-(2,5- dichlorobenzyl)- octahydropyrr...)
Show SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CC2CN(Cc3cc(Cl)ccc3Cl)CC2C1
Show InChI InChI=1S/C18H17Cl3N4O3/c19-13-1-2-14(20)10(3-13)4-23-5-11-7-24(8-12(11)6-23)18(28)25-9-15(21)16(22-25)17(26)27/h1-3,9,11-12H,4-8H2,(H,26,27)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483691
PNG
(4-chloro-1-(5-(3-(4- chlorophenoxy)- benzyl)- octa...)
Show SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CC2CN(Cc3cccc(Oc4ccc(Cl)cc4)c3)CC2C1
Show InChI InChI=1S/C24H22Cl2N4O4/c25-18-4-6-19(7-5-18)34-20-3-1-2-15(8-20)9-28-10-16-12-29(13-17(16)11-28)24(33)30-14-21(26)22(27-30)23(31)32/h1-8,14,16-17H,9-13H2,(H,31,32)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

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Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483692
PNG
(4-chloro-1-(2-(4- (pyrrolidin-1-yl)-2- (trifluorom...)
Show SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CCC2(CCN(Cc3ccc(cc3C(F)(F)F)N3CCCC3)C2)CC1
Show InChI InChI=1S/C25H29ClF3N5O3/c26-20-15-34(30-21(20)22(35)36)23(37)33-11-6-24(7-12-33)5-10-31(16-24)14-17-3-4-18(32-8-1-2-9-32)13-19(17)25(27,28)29/h3-4,13,15H,1-2,5-12,14,16H2,(H,35,36)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

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Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483707
PNG
(1-(2-((3- (trifluoromethyl)- [1,1'-biphenyl]-4- yl...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1CCC2(CCN(Cc3ccc(cc3C(F)(F)F)-c3ccccc3)C2)CC1
Show InChI InChI=1S/C27H27F3N4O3/c28-27(29,30)22-16-20(19-4-2-1-3-5-19)6-7-21(22)17-32-13-9-26(18-32)10-14-33(15-11-26)25(37)34-12-8-23(31-34)24(35)36/h1-8,12,16H,9-11,13-15,17-18H2,(H,35,36)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483694
PNG
(4-chloro-1-(5-(4- (pyrrolidin-1-yl)-2- (trifluorom...)
Show SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CC2CN(Cc3ccc(cc3C(F)(F)F)N3CCCC3)CC2C1
Show InChI InChI=1S/C23H25ClF3N5O3/c24-19-13-32(28-20(19)21(33)34)22(35)31-11-15-9-29(10-16(15)12-31)8-14-3-4-17(30-5-1-2-6-30)7-18(14)23(25,26)27/h3-4,7,13,15-16H,1-2,5-6,8-12H2,(H,33,34)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483695
PNG
(1-(5-((2- chlorobenzyl)oxy)- octahydrocyclopenta- ...)
Show SMILES OC(=O)c1nn(cc1C(F)(F)F)C(=O)N1CC2CC(CC2C1)OCc1ccccc1Cl
Show InChI InChI=1S/C20H19ClF3N3O4/c21-16-4-2-1-3-11(16)10-31-14-5-12-7-26(8-13(12)6-14)19(30)27-9-15(20(22,23)24)17(25-27)18(28)29/h1-4,9,12-14H,5-8,10H2,(H,28,29)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483716
PNG
(1-(4-(2-morpholino- 3-(trifluoromethyl)- benzyl)pi...)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CCN(Cc2cccc(c2N2CCOCC2)C(F)(F)F)CC1
Show InChI InChI=1S/C21H25F3N6O3/c22-21(23,24)16-3-1-2-15(18(16)28-10-12-33-13-11-28)14-27-6-8-29(9-7-27)20(32)30-5-4-17(26-30)19(25)31/h1-5H,6-14H2,(H2,25,31)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483697
PNG
(1-(2-(5-chloro-2- (trifluoromethyl)- benzyl)-2,8- ...)
Show SMILES OC(=O)c1nn(cc1C(F)(F)F)C(=O)N1CCC2(CCN(Cc3cc(Cl)ccc3C(F)(F)F)C2)CC1
Show InChI InChI=1S/C22H21ClF6N4O3/c23-14-1-2-15(21(24,25)26)13(9-14)10-31-6-3-20(12-31)4-7-32(8-5-20)19(36)33-11-16(22(27,28)29)17(30-33)18(34)35/h1-2,9,11H,3-8,10,12H2,(H,34,35)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483700
PNG
(1-(trans-5-((3- (trifluoromethyl)- benzyl)oxy)- oc...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1C[C@@H]2C[C@H](C[C@@H]2C1)OCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H20F3N3O4/c21-20(22,23)15-3-1-2-12(6-15)11-30-16-7-13-9-25(10-14(13)8-16)19(29)26-5-4-17(24-26)18(27)28/h1-6,13-14,16H,7-11H2,(H,27,28)/t13-,14+,16+
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483684
PNG
(1-(4-(3-(4- chlorophenoxy)- benzyl)- piperazine-1-...)
Show SMILES Cc1cn(nc1C(O)=O)C(=O)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1
Show InChI InChI=1S/C23H23ClN4O4/c1-16-14-28(25-21(16)22(29)30)23(31)27-11-9-26(10-12-27)15-17-3-2-4-20(13-17)32-19-7-5-18(24)6-8-19/h2-8,13-14H,9-12,15H2,1H3,(H,29,30)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

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Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483704
PNG
(1-(2-(3,5- dichlorobenzyl)-2,8- diazaspiro[4.5]- d...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1CCC2(CCN(Cc3cc(Cl)cc(Cl)c3)C2)CC1
Show InChI InChI=1S/C20H22Cl2N4O3/c21-15-9-14(10-16(22)11-15)12-24-6-2-20(13-24)3-7-25(8-4-20)19(29)26-5-1-17(23-26)18(27)28/h1,5,9-11H,2-4,6-8,12-13H2,(H,27,28)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483711
PNG
(1-(4-((4- (trifluoromethyl)- pyridin-3- yl)methyl)...)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CCN(Cc2cnccc2C(F)(F)F)CC1
Show InChI InChI=1S/C16H17F3N6O2/c17-16(18,19)12-1-3-21-9-11(12)10-23-5-7-24(8-6-23)15(27)25-4-2-13(22-25)14(20)26/h1-4,9H,5-8,10H2,(H2,20,26)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483681
PNG
(1-(5-(3-chloro-5- (trifluoromethyl)- benzyl)- octa...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1CC2CN(Cc3cc(Cl)cc(c3)C(F)(F)F)CC2C1
Show InChI InChI=1S/C19H18ClF3N4O3/c20-15-4-11(3-14(5-15)19(21,22)23)6-25-7-12-9-26(10-13(12)8-25)18(30)27-2-1-16(24-27)17(28)29/h1-5,12-13H,6-10H2,(H,28,29)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483680
PNG
(1-(5-(3-(4- chlorophenoxy)- benzyl)- octahydropyrr...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1CC2CN(Cc3cccc(Oc4ccc(Cl)cc4)c3)CC2C1
Show InChI InChI=1S/C24H23ClN4O4/c25-19-4-6-20(7-5-19)33-21-3-1-2-16(10-21)11-27-12-17-14-28(15-18(17)13-27)24(32)29-9-8-22(26-29)23(30)31/h1-10,17-18H,11-15H2,(H,30,31)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

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Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483679
PNG
(4-chloro-1-(4-((5- chloro-2- (trifluoromethyl)- be...)
Show SMILES CN(Cc1cc(Cl)ccc1C(F)(F)F)C1CCN(CC1)C(=O)n1cc(Cl)c(n1)C(O)=O
Show InChI InChI=1S/C19H19Cl2F3N4O3/c1-26(9-11-8-12(20)2-3-14(11)19(22,23)24)13-4-6-27(7-5-13)18(31)28-10-15(21)16(25-28)17(29)30/h2-3,8,10,13H,4-7,9H2,1H3,(H,29,30)
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483702
PNG
(1-(trans-5-((2- methyl-3- (trifluoromethyl)- benzy...)
Show SMILES Cc1c(CO[C@@H]2C[C@H]3CN(C[C@H]3C2)C(=O)n2ccc(n2)C(O)=O)cccc1C(F)(F)F
Show InChI InChI=1S/C21H22F3N3O4/c1-12-13(3-2-4-17(12)21(22,23)24)11-31-16-7-14-9-26(10-15(14)8-16)20(30)27-6-5-18(25-27)19(28)29/h2-6,14-16H,7-11H2,1H3,(H,28,29)/t14-,15+,16+
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LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483676
PNG
(1-(4-(3-(4- chlorophenoxy)- benzyl)- piperazine-1-...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1
Show InChI InChI=1S/C22H21ClN4O4/c23-17-4-6-18(7-5-17)31-19-3-1-2-16(14-19)15-25-10-12-26(13-11-25)22(30)27-9-8-20(24-27)21(28)29/h1-9,14H,10-13,15H2,(H,28,29)
MMDB

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n/an/a 550n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483673
PNG
(1-(2-methyl-4-((3- methyl-[1,1'- biphenyl]-4- yl)m...)
Show SMILES CC1CN(Cc2ccc(cc2C)-c2ccccc2)CCN1C(=O)n1ccc(n1)C(O)=O
Show InChI InChI=1S/C24H26N4O3/c1-17-14-20(19-6-4-3-5-7-19)8-9-21(17)16-26-12-13-27(18(2)15-26)24(31)28-11-10-22(25-28)23(29)30/h3-11,14,18H,12-13,15-16H2,1-2H3,(H,29,30)
MMDB

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n/an/a 550n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483671
PNG
(1-(4-(3-(3- chlorophenoxy)- benzyl)- piperazine-1-...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1CCN(Cc2cccc(Oc3cccc(Cl)c3)c2)CC1
Show InChI InChI=1S/C22H21ClN4O4/c23-17-4-2-6-19(14-17)31-18-5-1-3-16(13-18)15-25-9-11-26(12-10-25)22(30)27-8-7-20(24-27)21(28)29/h1-8,13-14H,9-12,15H2,(H,28,29)
MMDB

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n/an/a 550n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483669
PNG
(1-(4-((5-chloro-2- (trifluoromethyl)- benzyl)- (me...)
Show SMILES CN(Cc1cc(Cl)ccc1C(F)(F)F)C1CCN(CC1)C(=O)n1ccc(n1)C(O)=O
Show InChI InChI=1S/C19H20ClF3N4O3/c1-25(11-12-10-13(20)2-3-15(12)19(21,22)23)14-4-7-26(8-5-14)18(30)27-9-6-16(24-27)17(28)29/h2-3,6,9-10,14H,4-5,7-8,11H2,1H3,(H,28,29)
MMDB

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n/an/a 550n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483666
PNG
(1-(4-(3-((5- (trifluoromethyl)- pyridin-2- yl)oxy)...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1CCN(Cc2cccc(Oc3ccc(cn3)C(F)(F)F)c2)CC1
Show InChI InChI=1S/C22H20F3N5O4/c23-22(24,25)16-4-5-19(26-13-16)34-17-3-1-2-15(12-17)14-28-8-10-29(11-9-28)21(33)30-7-6-18(27-30)20(31)32/h1-7,12-13H,8-11,14H2,(H,31,32)
MMDB

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n/an/a 550n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483665
PNG
(1-(4-(3-((4- (trifluoromethyl)- pyridin-2- yl)oxy)...)
Show SMILES OC(=O)c1ccn(n1)C(=O)N1CCN(Cc2cccc(Oc3cc(ccn3)C(F)(F)F)c2)CC1
Show InChI InChI=1S/C22H20F3N5O4/c23-22(24,25)16-4-6-26-19(13-16)34-17-3-1-2-15(12-17)14-28-8-10-29(11-9-28)21(33)30-7-5-18(27-30)20(31)32/h1-7,12-13H,8-11,14H2,(H,31,32)
MMDB

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n/an/a 550n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483715
PNG
(1-(2-(2-chloro-4- morpholinobenzyl)- 2,8-diazaspir...)
Show SMILES NC(=O)c1ccn(n1)C(=O)N1CCC2(CCN(Cc3ccc(cc3Cl)N3CCOCC3)C2)CC1
Show InChI InChI=1S/C24H31ClN6O3/c25-20-15-19(29-11-13-34-14-12-29)2-1-18(20)16-28-8-4-24(17-28)5-9-30(10-6-24)23(33)31-7-3-21(27-31)22(26)32/h1-3,7,15H,4-6,8-14,16-17H2,(H2,26,32)
MMDB

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n/an/a 550n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
Fatty acid 2-hydroxylase


(Human)
BDBM483663
PNG
(4-chloro-1-(4-(((5- chloro-2- (trifluoromethyl)- b...)
Show SMILES CN(CC1CCN(CC1)C(=O)n1cc(Cl)c(n1)C(O)=O)Cc1cc(Cl)ccc1C(F)(F)F
Show InChI InChI=1S/C20H21Cl2F3N4O3/c1-27(10-13-8-14(21)2-3-15(13)20(23,24)25)9-12-4-6-28(7-5-12)19(32)29-11-16(22)17(26-29)18(30)31/h2-3,8,11-12H,4-7,9-10H2,1H3,(H,30,31)
MMDB

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n/an/a 550n/an/an/an/an/an/a



LUNDBECK LA JOLLA RESEARCH CENTER, INC.

US Patent


Assay Description
Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...


US Patent US10927105 (2021)

More data for this
Ligand-Target Pair
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