Compile Data Set for Download or QSAR
maximum 50k data
Found 2789 of ic50 for UniProtKB: A0A024R5S8
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  0.00400nMAssay Description:Inhibition of aromatase (unknown origin) transfected in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50539776(CHEMBL4639677)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50539777(CHEMBL4632445)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50337121(2-chloro-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triaz...)
Affinity DataIC50:  0.0150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50337123(4-(((6-cyano-4'-methoxybiphenyl-3-yl)(4H-1,2,4-tri...)
Affinity DataIC50:  0.0150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50337122(2-bromo-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazo...)
Affinity DataIC50:  0.0180nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  0.0300nMAssay Description:Aromatase inhibitor potency as iron-binding-related type II difference spectrumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50337118(5'-((4-bromobenzyl)(4H-1,2,4-triazol-4-yl)amino)-2...)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50592781(CHEMBL5203413)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50337117(5'-(benzyl(4H-1,2,4-triazol-4-yl)amino)-2'-cyanobi...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50307918(2-(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50123025(CHEMBL3623231)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione as substrate after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM10007(4-[(6-methoxy-1-benzofuran-2-yl)(1H-1,2,4-triazol-...)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM10016(4-{[(4-bromophenyl)methyl](4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of aromatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50525257(CHEMBL4520995)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM10004(1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50307901(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hyd...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50337120(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50307901(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hyd...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM24341(4-{[(4-chloro-3-hydroxyphenyl)methyl](4H-1,2,4-tri...)
Affinity DataIC50:  0.180nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50123026(CHEMBL3623232)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of aromatase in human JEG3 cells using [1beta-3H] androstenedione as substrate assessed as tritiated H2O release after 1 hr by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50123026(CHEMBL3623232)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione as substrate after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50525260(CHEMBL4465348)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50307900(5-((1H-1,2,4-triazol-1-yl)methyl)-4'-hydroxybiphen...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50307899(5-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-2-carbon...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50337119(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50307902(5-((1H-1,2,4-triazol-1-yl)methyl)-4'-chloro-3'-hyd...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50307919(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chlorobipheny...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50121079(CHEMBL3622064)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50121079(CHEMBL3622064)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50121079(CHEMBL3622064)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50121105(CHEMBL3622055)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50121105(CHEMBL3622055)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50121095(CHEMBL3622054)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50307881(3'-((1H-1,2,4-triazol-1-yl)methyl)-3-chloro-5'-(2-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM24328(4-{[(4-hydroxy-3-iodophenyl)methyl](4H-1,2,4-triaz...)
Affinity DataIC50:  0.330nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50307882(5'-((1H-1,2,4-triazol-1-yl)methyl)-4-chloro-2'-cya...)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50592778(CHEMBL5175340)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM10016(4-{[(4-bromophenyl)methyl](4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM24344(4-({[3-hydroxy-4-(trifluoromethyl)phenyl]methyl}(4...)
Affinity DataIC50:  0.400nMAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50121073(CHEMBL3622056)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50460601(CHEMBL4227385)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50121074(CHEMBL3622057)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50592775(CHEMBL5184004)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM10005(1-[(4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50337124(4-(((6-cyano-4'-fluorobiphenyl-3-yl)(4H-1,2,4-tria...)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50307916(2-(5-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-3-yl)...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM24342(4-{[(4-bromo-3-hydroxyphenyl)methyl](4H-1,2,4-tria...)
Affinity DataIC50:  0.5nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
State University Of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM10016(4-{[(4-bromophenyl)methyl](4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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