Affinity DataEC50: 0.0900nMAssay Description:Agonist activity at human S1P4 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at S1P4 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at S1P4 receptor (unknown origin) measured after 45 mins by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at S1P4 receptor (unknown origin) measured after 45 mins by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.600nMpH: 7.4Assay Description:Agonism of human S1P-4 receptor expressed in CHO cells, 90-120 min in pH 7.4 using [35S]-GTP-gammaS as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Agonist activity at human S1P4 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.920nMAssay Description:Agonist activity at S1P4 receptor (unknown origin) measured after 45 mins by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.920nMAssay Description:Agonist activity at S1P4 receptor (unknown origin) measured after 45 mins by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Binding potency at human S1P4 receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Binding potency at human S1P4 receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at recombinant human S1P4 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human recombinant S1P4 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMpH: 7.4Assay Description:Agonism of human S1P-4 receptor expressed in CHO cells, 90-120 min in pH 7.4 using [35S]-GTP-gammaS as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 3.40nMAssay Description:Agonist activity at human recombinant S1P4 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.60nMAssay Description:Agonist activity at human S1P4R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.60nMAssay Description:Agonist activity at human S1P4R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 5.39nMAssay Description:Agonist activity at human S1P4 receptor assessed as effect on calcium mobilization by Gq dependent whole cell assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.39nMAssay Description:Agonist activity at human S1P4 receptor assessed as effect on calcium mobilization by Gq dependent whole cell assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.60nMAssay Description:Agonist activity at recombinant human S1P4 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.70nMAssay Description:Agonist activity at human S1P4 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 7.40nMAssay Description:Activity at human recombinant S1P4 receptor expressed in CHO cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.40nMAssay Description:Agonist activity at S1P4 receptor in human U2OS cells expressing VP16-GAL4 transcriptional factor and beta-arrestin/TEV protease fusion protein asses...More data for this Ligand-Target Pair
Affinity DataEC50: 7.90nMAssay Description:Activity at human recombinant S1P4 receptor expressed in CHO cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at S1P4 receptor in human U2OS cells expressing VP16-GAL4 transcriptional factor and beta-arrestin/TEV protease fusion protein asses...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at recombinant human S1P4 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at recombinant human S1P4 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human S1P4 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human recombinant S1P4 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human S1P4R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 16.0nMAssay Description:Agonist activity at human S1P4 receptor assessed as effect on calcium mobilization by Gq dependent whole cell assayMore data for this Ligand-Target Pair
Affinity DataEC50: 16.8nMAssay Description:Activity at human recombinant S1P4 receptor expressed in CHO cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 18.6nMAssay Description:Activity at human recombinant S1P4 receptor expressed in CHO cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Agonist activity at human S1P4 receptor expressed in CHO cells assessed as induction of [S35]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Binding potency at human S1P4 receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Agonist activity at recombinant human S1P4 receptor expressed in Chem-1 cells assessed as calcium flux measured for 180 secs by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 22.2nMAssay Description:Agonist activity at human S1P4 receptor assessed as effect on calcium mobilization by Gq dependent whole cell assayMore data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Agonist activity at human S1P4 receptor by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
Affinity DataEC50: 33.1nMAssay Description:Activity at human recombinant S1P4 receptor expressed in CHO cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 36nMAssay Description:In vitro binding affinity towards human Sphingosine 1-phosphate receptor 4 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...More data for this Ligand-Target Pair
Affinity DataEC50: 36nMAssay Description:Agonist activity at S1P4 receptor in human U2OS cells expressing VP16-GAL4 transcriptional factor and beta-arrestin/TEV protease fusion protein asses...More data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:In vitro binding affinity towards human Sphingosine 1-phosphate receptor 4 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...More data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Agonist activity at recombinant human S1PR4 expressed in CHO cell membranes assessed as [35S]GTP-gammaS binding measured after 1.5 hrs by TopCount sc...More data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Effective concentration against sphingosine 1-phosphate receptor 4 determined by a [c-35S]-GTP binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Agonist activity at human S1P4R expressed in human U2OS cells containing EDG6 gene co-expressing GAL4-VP16 and beta-arrestin/TEV protease assessed as...More data for this Ligand-Target Pair
Affinity DataEC50: 45.5nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Agonist activity at human S1P4R expressed in human U2OS cells containing EDG6 gene co-expressing GAL4-VP16 and beta-arrestin/TEV protease assessed as...More data for this Ligand-Target Pair
Affinity DataEC50: 46.3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
Affinity DataEC50: 48nMAssay Description:In vitro binding affinity towards human Sphingosine 1-phosphate receptor 4 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...More data for this Ligand-Target Pair
Affinity DataEC50: 52nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair