Affinity DataEC50: 0.390nMAssay Description:Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...More data for this Ligand-Target Pair
Affinity DataEC50: 0.390nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at GFP-tagged rat kappa opioid receptor expressed in HEK293 cells assessed as increase in ERK1/2 phosphorylation after 5 mins by Wes...More data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Binding affinity to rat brain opioid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.540nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 0.600nMAssay Description:Binding affinity to opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 0.650nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Binding affinity to opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Binding affinity to rat brain opioid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Binding affinity to opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 1.24nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Displacement of [3H]dalamid ([D-Ala2,Met5] enkephalinamide) from opioid receptors of rat brain membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Binding affinity to rat brain opioid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Binding affinity to rat brain opioid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Binding affinity to opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Displacement of radiolabeled dihydromorphine from opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Displacement of radiolabeled dihydromorphine from opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Displacement of [3H]dalamid ([D-Ala2,Met5] enkephalinamide) from opioid receptors of rat brain membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Binding affinity to opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Binding affinity to opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Binding affinity to rat brain opioid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 3.56nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Displacement of radiolabeled dihydromorphine from opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 4.19nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Agonist activity at GFP-tagged rat kappa opioid receptor expressed in HEK293 cells assessed as increase in beta-arrestin mediated p38 phosphorylation...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Displacement of [3H]dalamid ([D-Ala2,Met5] enkephalinamide) from opioid receptors of rat brain membraneMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Displacement of [3H]dalamid ([D-Ala2,Met5] enkephalinamide) from opioid receptors of rat brain membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Effective concentration to inhibit E203Q,D204N,D206N KL-2 Opioid receptor kappa 1 binding to [35S]GTP-gamma-S, expressed in COS cellsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Displacement of [3H]dalamid ([D-Ala2,Met5] enkephalinamide) from opioid receptors of rat brain membraneMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Displacement of [3H]dalamid ([D-Ala2,Met5] enkephalinamide) from opioid receptors of rat brain membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 7.70nMAssay Description:Agonist activity at rat kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Effective concentration to inhibit D216,ND217N,E218Q KL-2 Opioid receptor kappa 1 binding to [35S]GTP-gamma-S, expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 8.30nMAssay Description:Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...More data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Displacement of radiolabeled dihydromorphine from opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Displacement of radiolabeled dihydromorphine from opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Binding affinity to opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Displacement of radiolabeled dihydromorphine from opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Effective concentration to inhibit wild type KL-2 Opioid receptor kappa 1 binding to [35S]GTP-gamma-S, expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Binding affinity to opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillat...More data for this Ligand-Target Pair
Affinity DataEC50: 29.4nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 36.5nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataEC50: 46.9nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Displacement of [3H]dalamid ([D-Ala2,Met5] enkephalinamide) from opioid receptors of rat brain membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Binding affinity to opioid receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 72.4nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataEC50: 90nMAssay Description:Displacement of [3H]dalamid ([D-Ala2,Met5] enkephalinamide) from opioid receptors of rat brain membraneMore data for this Ligand-Target Pair