Compile Data Set for Download or QSAR
maximum 50k data
Found 448 of ic50 data for polymerid = 379
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223491(US10407441, Compound JQ6 | US10925881, Name (S)-JQ...)
Affinity DataIC50:  0.240nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223492(US10407441, Compound JQ8 | US10925881, Name (S)-JQ...)
Affinity DataIC50:  0.427nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223493(US10407441, Compound JQ13 | US10925881, Name (S)-J...)
Affinity DataIC50:  0.584nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM259884(US10308662, Compound 125 | US9505780, 125)
Affinity DataIC50:  1.87nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249313(US9458145, 1020-289)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249309(US10017501, Compound 1020-114 | US9458145, 1020-11...)
Affinity DataIC50:  2.70nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249314(US10017501, Compound 1020-298 | US9458145, 1020-29...)
Affinity DataIC50:  3.60nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249312(US10017501, Compound 1020-257 | US9458145, 1020-25...)
Affinity DataIC50:  5.60nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249311(US10017501, Compound 1020-239 | US9458145, 1020-23...)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223495(US10407441, Compound JQ35 | US9320741, JQ35)
Affinity DataIC50:  6.13nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249306(US10017501, Compound 1020-104 | US9458145, 1020-10...)
Affinity DataIC50:  11.7nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249305(US10017501, Compound 1020-103 | US9458145, 1020-10...)
Affinity DataIC50:  12.4nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249308(US10017501, Compound 1020-113 | US9458145, 1020-11...)
Affinity DataIC50:  12.8nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249307(US10017501, Compound 1020-112 | US9458145, 1020-11...)
Affinity DataIC50:  13.5nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50365262((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)
Affinity DataIC50:  14nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249310(US10017501, Compound 1020-224 | US9458145, 1020-22...)
Affinity DataIC50:  20.2nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM223494(US10407441, Compound JQ33 | US9320741, JQ33)
Affinity DataIC50:  29.5nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM259897(US9505780, JQ-1)
Affinity DataIC50:  39.1nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249283(US10017501, Compound 1020-57 | US9458145, 1020-57)
Affinity DataIC50:  54.4nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249283(US10017501, Compound 1020-57 | US9458145, 1020-57)
Affinity DataIC50:  54.4nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249287(US10017501, Compound 1020-77 | US9458145, 1020-77)
Affinity DataIC50:  64.8nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249287(US10017501, Compound 1020-77 | US9458145, 1020-77)
Affinity DataIC50:  64.8nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249279(US10017501, Compound 1020-28 | US9458145, 1020-28)
Affinity DataIC50:  65.5nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249279(US10017501, Compound 1020-28 | US9458145, 1020-28)
Affinity DataIC50:  65.5nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249284(US10017501, Compound 1020-72 | US9458145, 1020-72)
Affinity DataIC50:  69.1nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249284(US10017501, Compound 1020-72 | US9458145, 1020-72)
Affinity DataIC50:  69.1nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249276(US10017501, Compound 1020-12 | US9458145, 1020-12)
Affinity DataIC50:  69.2nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249276(US10017501, Compound 1020-12 | US9458145, 1020-12)
Affinity DataIC50:  69.2nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249297(US10017501, Compound 1020-102 | US9458145, 1020-10...)
Affinity DataIC50:  75.7nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249297(US10017501, Compound 1020-102 | US9458145, 1020-10...)
Affinity DataIC50:  75.7nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249298(US10017501, Compound 1020-120 | US9458145, 1020-12...)
Affinity DataIC50:  76.1nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249298(US10017501, Compound 1020-120 | US9458145, 1020-12...)
Affinity DataIC50:  76.1nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM404272(US10017501, Compound 1020-75)
Affinity DataIC50:  78.2nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249286(US9458145, 1020-75)
Affinity DataIC50:  78.2nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)
Affinity DataIC50:  78.6nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)
Affinity DataIC50:  78.6nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249299(US10017501, Compound 1020-121 | US9458145, 1020-12...)
Affinity DataIC50:  80.8nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249299(US10017501, Compound 1020-121 | US9458145, 1020-12...)
Affinity DataIC50:  80.8nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249289(US10017501, Compound 1020-79 | US9458145, 1020-79)
Affinity DataIC50:  87.2nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249289(US10017501, Compound 1020-79 | US9458145, 1020-79)
Affinity DataIC50:  87.2nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249288(US10017501, Compound 1020-78 | US9458145, 1020-78)
Affinity DataIC50:  94.1nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249288(US10017501, Compound 1020-78 | US9458145, 1020-78)
Affinity DataIC50:  94.1nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249296(US10017501, Compound 1020-96 | US9458145, 1020-96)
Affinity DataIC50:  96.9nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249296(US10017501, Compound 1020-96 | US9458145, 1020-96)
Affinity DataIC50:  96.9nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249273(US10017501, Compound 1020-1 | US9458145, 1020-1)
Affinity DataIC50:  97.6nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM249273(US10017501, Compound 1020-1 | US9458145, 1020-1)
Affinity DataIC50:  97.6nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM313771(US10167292, Example 5)
Affinity DataIC50: <100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM313773(US10167292, Example 7)
Affinity DataIC50: <100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM313774(US10167292, Example 8)
Affinity DataIC50: <100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM313775(US10167292, Example 10)
Affinity DataIC50: <100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 448 total ) | Next | Last >>
Jump to: