Affinity DataIC50: 25.5nM Kd: 35nMpH: 7.5Assay Description:In vitro activity assay using various kinases.More data for this Ligand-Target Pair
Affinity DataIC50: 710nM Kd: 760nMpH: 7.0Assay Description:In vitro kinase activity and selectivity was determined by using SelectScreen kinase profiling Z'-LYTE assay from Invitrogen.More data for this Ligand-Target Pair
Affinity DataKd: 1.16E+3nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 180nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKd: 0.100nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKd: 1.16E+3nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKd: 36nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKd: 23nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKd: 21nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKd: 1nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKd: 0.0900nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKd: 0.5nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKd: 0.100nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
Affinity DataKd: 12nMpH: 7.6Assay Description:Activation of p38 kinase assay was measured by fluorescence emission using a Perkin-Elmer LS 50B fluorimeter.More data for this Ligand-Target Pair
Affinity DataKd: 55nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
Affinity DataKd: 197nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
Affinity DataKd: 495nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
Affinity DataKd: 9.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 7.10E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 170nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...More data for this Ligand-Target Pair
Affinity DataKd: 2.80nMAssay Description:Kinase enzyme binding activities of the compound disclosed herein may be determined using a proprietary assay which measures active site-directed com...More data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataKd: 2.5nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataKd: 9.40nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataKd: 0.0970nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataKd: 22nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataKd: 23nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataKd: 5.90nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to p38alphaMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to p38-alphaMore data for this Ligand-Target Pair
Affinity DataKd: 120nMAssay Description:Binding affinity to TGFBR1More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to TGFBR1More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to p38-alphaMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for TGFBR1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 4.20E+3nMAssay Description:Binding constant for TGFBR1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding constant for TGFBR1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for p38-alpha kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 120nMAssay Description:Binding constant for TGFBR1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for p38-alpha kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for p38-alpha kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for p38-alpha kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding constant for TGFBR1 kinase domainMore data for this Ligand-Target Pair
