Affinity DataEC50: 0.110nMAssay Description:Agonist activity at TLR2 in human cells by cell based assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 0.260nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 0.280nMAssay Description:Agonist activity at TLR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.281nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at TLR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.304nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 0.380nMAssay Description:Agonist activity at TLR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.383nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 0.450nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 0.468nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 0.470nMAssay Description:Agonist activity at TLR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.560nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 0.609nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 0.870nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 1.01nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 1.47nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 1.55nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 1.64nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
Affinity DataEC50: 1.86nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 1.95nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 2.11nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 3.23nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 3.63nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
Affinity DataEC50: 3.70nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
Affinity DataEC50: 3.80nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
Affinity DataEC50: 4.40nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 4.44nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 4.5nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
Affinity DataEC50: 4.79nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
Affinity DataEC50: 4.90nMAssay Description:Agonist activity at TLR2 in HEK-Blue hTLR2 cells assessed as NF-kappaB activation preincubated for 24 hrs followed by replacement of medium containin...More data for this Ligand-Target Pair
Affinity DataEC50: 5.52nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NFkappaB translocation after 12 hrs by secretory alkaline phosphatase reporter g...More data for this Ligand-Target Pair
Affinity DataEC50: 6.48nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
Affinity DataEC50: 34nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
Affinity DataEC50: 48nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 56nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
Affinity DataEC50: 61.5nMAssay Description:The induction of NF-κB in a TLR2-specific reporter gene assay was quantified using HEK-BLUE™ cells as previously described (Wu, W. et al., ...More data for this Ligand-Target Pair
Affinity DataEC50: 78nMAssay Description:Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB signaling after 24 hrs by luminescence based luciferase r...More data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Agonist activity at TLR2 in HEK-Blue cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 151nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells co-expressing NF-kappaB-SEAP reporter gene measured after 16 hrs by SEAP reporter gene ass...More data for this Ligand-Target Pair
