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Found 217 of ic50 for UniProtKB: P00766
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50118029(3-Isopropyl-1-methanesulfonyl-4-(4-piperidin-1-yl-...)
Affinity DataIC50:  22nMAssay Description:The compound was evaluated for its inhibitory activity against Chymotrypsinogen using selectivity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058977(3-Benzoyl-1-phenyl-imidazolidine-2,4-dione | CHEMB...)
Affinity DataIC50:  48nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50093745((6R,7R)-7-(2-Ethoxy-benzoylamino)-7-methoxy-3-(1-m...)
Affinity DataIC50:  160nMAssay Description:Inhibitory concentration of the compound was measured against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50059002(3-(4-Chloro-benzenesulfonyl)-1-(3-chloro-phenyl)-i...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50059013(3-(4-Chloro-benzoyl)-1-phenyl-imidazolidine-2,4-di...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50312532(CHEMBL1077010 | molassamide)
Affinity DataIC50:  234nMAssay Description:Inhibition of bovine pancreas alpha-chymotrypsin preincubated for 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50059011(3-(4-Chloro-benzenesulfonyl)-1-(4-chloro-phenyl)-i...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50118030(4-(5-Cyclopropylaminomethyl-pyrazine-2-carbonyl)-3...)
Affinity DataIC50:  540nMAssay Description:The compound was evaluated for its inhibitory activity against Chymotrypsinogen using selectivity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058975(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  730nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50066999((S)-3,3-Diethyl-2-[4-(4-methyl-piperazine-1-carbon...)
Affinity DataIC50:  980nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50459614(CHEMBL4212843)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of bovine pancreas alpha-chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate incubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50059012(3-(4-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058997(1-Phenyl-3-(toluene-2-sulfonyl)-imidazolidine-2,4-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058993(3-(2-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50059009(3-Benzenesulfonyl-1-phenyl-imidazolidine-2,4-dione...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058967(3-(3-Phenoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058965(3-[3-(4-Methyl-piperazine-1-carbonyl)-benzenesulfo...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50070010(4-((2R,3R)-1-Benzylcarbamoyl-3-methyl-4-oxo-azetid...)
Affinity DataIC50:  1.60E+3nMAssay Description:Concentration of the compound required to inhibit the mammalian Chymotrypsinogen by 50% was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058994(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50059007(4-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058964(3-(3,4-Dimethyl-benzenesulfonyl)-1-phenyl-imidazol...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50459616(CHEMBL4217798)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of bovine pancreas alpha-chymotrypsin using N-succinyl-Gly-Gly-Phe-p-nitroanilide as substrate incubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50085342(CHEMBL61059 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsin(alpha-CT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50065899((2S,3S)-2-Benzyl-3-methylsulfanyl-4-oxo-azetidine-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Compound was tested for its activity against bovine pancreatic Alpha-chymotrypsin (BPC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50085366(CHEMBL292834 | N-((S)-1-Benzyl-3-chloro-2-oxo-prop...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsin(alpha-CT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50059005(3-(4-Bromo-benzenesulfonyl)-1-phenyl-imidazolidine...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058998(3-(4-Fluoro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50085356(CHEMBL61933 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsin(alpha-CT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50118028(3-Isopropyl-1-methanesulfonyl-4-(2-pyrrolidin-1-yl...)
Affinity DataIC50:  3.00E+3nMAssay Description:The compound was evaluated for its inhibitory activity against Chymotrypsinogen using selectivity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of bovine pancreas alpha-chymotrypsin using KSp21 as substrate preincubated for 30 mins followed by substrate addition measured after 50 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50059003(3-(3,4-Dichloro-benzenesulfonyl)-1-(3,4-dichloro-p...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058983(3-(3-Methoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058973(3-(3,4-Dichloro-benzenesulfonyl)-1-phenyl-imidazol...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50066998((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  4.00E+3nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058996(3-(4-Chloro-benzenesulfonyl)-1-(3,4-dichloro-pheny...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50015857(3-Acetoxymethyl-5,5,8-trioxo-7-phenylacetoxy-5lamb...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of alpha-chymotrypsin enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058971(CHEMBL304338 | [3-(2,5-Dioxo-3-phenyl-imidazolidin...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50085346(CHEMBL294290 | N-((S)-1-Benzyl-3-chloro-2-oxo-prop...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsin(alpha-CT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50066996((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  4.86E+3nMAssay Description:The compound was tested for inhibition of Chymotrypsinogen with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM26139(1-benzothiophen-2-ylboranediol | 1-benzothiophen-2...)
Affinity DataIC50:  5.00E+3nMAssay Description:Compound was tested for its specificity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50085361(CHEMBL59998 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsin(alpha-CT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50059006(3-(4-Methoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM222139(Chymostatin | US11859014, Compound chymostatin)
Affinity DataIC50:  5.80E+3nMpH: 7.6Assay Description:The α-chymotrypsin inhibition activity was evaluated in 50 mM Tris-HCl buffer pH 7.6 with 10 mM CaCl2. α-Chymotrypsin (bovine pancreas) at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50065866((2S,3S)-3-Allyl-2-benzyl-4-oxo-azetidine-1-carboxy...)
Affinity DataIC50:  6.00E+3nMAssay Description:Compound was tested for its activity against bovine pancreatic Alpha-chymotrypsin (BPC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058995(3-[4-(4-Methyl-piperazine-1-carbonyl)-benzenesulfo...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50289012(2-(2-Fluoro-phenyl)-benzo[d][1,3]oxazin-4-one | 2-...)
Affinity DataIC50:  6.50E+3nMpH: 7.6Assay Description:The α-chymotrypsin inhibition activity was evaluated in 50 mM Tris-HCl buffer pH 7.6 with 10 mM CaCl2. α-Chymotrypsin (bovine pancreas) at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50059004(1-Phenyl-3-(toluene-4-sulfonyl)-imidazolidine-2,4-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058989(3-(4-Nitro-benzenesulfonyl)-1-phenyl-imidazolidine...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058966(3-(4-Phenoxy-benzenesulfonyl)-1-phenyl-imidazolidi...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Gsk

Curated by ChEMBL
LigandPNGBDBM50058979(3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-be...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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