Target5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2(Homo sapiens (Human))
Vanderbilt University
Vanderbilt University
Affinity DataIC50: <1nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of full-length recombinant human GST and His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression system by LanthaScreen as...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of full-length recombinant human GST and His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression system by LanthaScreen as...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of full-length recombinant human GST and His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression system by LanthaScreen as...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of full-length recombinant human GST and His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression system by LanthaScreen as...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of human recombinant full length N-terminal GST/N-terminal His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 102nMAssay Description:Inhibition of AMPKalpha1beta1gamma1 (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 108nMAssay Description:Inhibition of AMPKalpha1beta1gamma1 (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 206nMAssay Description:Inhibition of human recombinant full length N-terminal GST/N-terminal His-tagged AMPK alpha2/beta1/gamma1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2(Homo sapiens (Human))
Vanderbilt University
Vanderbilt University
Affinity DataIC50: 235nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 235nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 318nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Activation of recombinant AMPKbeta1 in cryopreserved human hepatocytes assessed as reduction in 14C-2-acetic acid incorporation after 1 hr by scintil...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Activation of recombinant AMPKbeta1 in cryopreserved human hepatocytes assessed as reduction in 14C-2-acetic acid incorporation after 1 hr by scintil...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 527nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2(Homo sapiens (Human))
Vanderbilt University
Vanderbilt University
Affinity DataIC50: 1.12E+3nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2(Homo sapiens (Human))
Vanderbilt University
Vanderbilt University
Affinity DataIC50: 1.94E+3nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.94E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.92E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2(Homo sapiens (Human))
Vanderbilt University
Vanderbilt University
Affinity DataIC50: 3.53E+3nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 7.26E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2(Homo sapiens (Human))
Vanderbilt University
Vanderbilt University
Affinity DataIC50: 8.04E+3nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of AMPK A1/B1/G1 by FRET assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Activation of recombinant AMPKbeta1 in cryopreserved human hepatocytes assessed as reduction in 14C-2-acetic acid incorporation after 1 hr by scintil...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Activation of recombinant AMPKbeta1 in cryopreserved human hepatocytes assessed as reduction in 14C-2-acetic acid incorporation after 1 hr by scintil...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of AMPKB1More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of neuraminidase of influenza A/PR/8/34(H1N1)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of neuraminidase of influenza A/PR/8/34(H1N1)More data for this Ligand-Target Pair