Compile Data Set for Download or QSAR
maximum 50k data
Found 37 of ec50 for UniProtKB: A0A0M3M0G7
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50504091(CHEMBL4575618)
Affinity DataEC50:  79nMAssay Description:Inhibition of PD1/PDL1 interaction in human Jurkat cells co-cultured with human U2OS cells expressing PDL1 assessed as reduction in SHP1 recruitment ...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50573584(CHEMBL4845782)
Affinity DataEC50:  104nMAssay Description:Inhibition of PD1/PDL1 protein-protein interaction in human Jurkat cells overexpressing PD1 co-cultured with human Hep3B cells expressing PDL1 protei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50504093(CHEMBL4516321)
Affinity DataEC50:  219nMAssay Description:Inhibition of PD1/PDL1 interaction in human Jurkat cells co-cultured with human U2OS cells expressing PDL1 assessed as reduction in SHP1 recruitment ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50507503(CHEMBL4455806)
Affinity DataEC50:  293nMAssay Description:Inhibition of PD1/PDL1 interaction in human jurkat cells co-expressing TCR promoter assessed as TCR activation by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50504092(CHEMBL4525587)
Affinity DataEC50:  334nMAssay Description:Inhibition of PD1/PDL1 interaction in human Jurkat cells co-cultured with human U2OS cells expressing PDL1 assessed as reduction in SHP1 recruitment ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50580530(CHEMBL5092744)
Affinity DataEC50:  375nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in human Jurkat cells expressing PD-1/NFAT/Luc cocultured with CHO-K1 cells expressing PD-L1/aAPC assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50573586(CHEMBL4867169)
Affinity DataEC50:  376nMAssay Description:Inhibition of PD1/PDL1 protein-protein interaction in human Jurkat cells overexpressing PD1 co-cultured with human Hep3B cells expressing PDL1 protei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50570051(CHEMBL4874696)
Affinity DataEC50:  430nMAssay Description:Inhibition of PD-1/PD-L1 interaction in CHO cells expressing PD-Ll/TCR cocultured with human Jurkat cells expressing PD-1 assessed as activation of e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50507501(CHEMBL4576758)
Affinity DataEC50:  556nMAssay Description:Inhibition of PD1/PDL1 interaction in human jurkat cells co-expressing TCR promoter assessed as TCR activation by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50504091(CHEMBL4575618)
Affinity DataEC50:  763nMAssay Description:Inhibition of human PD1 stably expressed in human Jurkat T cells co-expressing NFAT-induced luciferase/human PDL1 stably expressed in CHOK1 cells co-...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50573585(CHEMBL4846412)
Affinity DataEC50:  775nMAssay Description:Inhibition of PD1/PDL1 protein-protein interaction in human Jurkat cells overexpressing PD1 co-cultured with human Hep3B cells expressing PDL1 protei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50535763(CHEMBL4473436)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of human PDL1 expressed in CHO-K1 cells co-expressing aAPC assessed as reduction in PDL1 interaction with human PD1 expressed in Jurkat T ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50576605(CHEMBL4862352)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of PD-1/PD-L1 interaction in human Jurkat cells cocultured with CHO cells expressing PD-Ll/TCRAct assessed as activation of effector Jurka...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM363080((R)-2-((2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1&#...)
Affinity DataEC50:  2.08E+3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in human Jurkat cells expressing PD-1/NFAT/Luc cocultured with CHO-K1 cells expressing PD-L1/aAPC assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50239947(CHEMBL4089730 | US20230303494, Compound BMS202 | U...)
Affinity DataEC50:  2.76E+3nMAssay Description:Inhibition of PD1/PDL1 interaction in human Jurkat cells co-cultured with human U2OS cells expressing PDL1 assessed as reduction in SHP1 recruitment ...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50570053(CHEMBL4875804)
Affinity DataEC50:  2.90E+3nMAssay Description:Inhibition of PD-1/PD-L1 interaction in CHO cells expressing PD-Ll/TCR cocultured with human Jurkat cells expressing PD-1 assessed as activation of e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50542954(CHEMBL4639202)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction in human PBMC-derived CD3-positive T cells co-cultured with human Hep3B cells expressing hum...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50504093(CHEMBL4516321)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of human PD1 stably expressed in human Jurkat T cells co-expressing NFAT-induced luciferase/human PDL1 stably expressed in CHOK1 cells co-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM363328(N-(2-((5-chloro-2-((3-cyanobenzyl)oxy)-4-((3-(2,3-...)
Affinity DataEC50: >3.30E+3nMAssay Description:Inhibition of PD-1/PD-L1 interaction in CHO cells expressing PD-Ll/TCR cocultured with human Jurkat cells expressing PD-1 assessed as activation of e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50504092(CHEMBL4525587)
Affinity DataEC50:  4.21E+3nMAssay Description:Inhibition of human PD1 stably expressed in human Jurkat T cells co-expressing NFAT-induced luciferase/human PDL1 stably expressed in CHOK1 cells co-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50507495(CHEMBL4445464)
Affinity DataEC50:  6.30E+3nMAssay Description:Inhibition of PD1/PDL1 interaction in human jurkat cells co-expressing TCR promoter assessed as TCR activation by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547282(CHEMBL4765124)
Affinity DataEC50:  6.60E+3nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547281(CHEMBL4749472)
Affinity DataEC50:  6.80E+3nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50535764(CHEMBL4456990)
Affinity DataEC50:  8.40E+3nMAssay Description:Inhibition of human PDL1 expressed in CHO-K1 cells co-expressing aAPC assessed as reduction in PDL1 interaction with human PD1 expressed in Jurkat T ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50535765(CHEMBL4578475)
Affinity DataEC50:  9.50E+3nMAssay Description:Inhibition of human PDL1 expressed in CHO-K1 cells co-expressing aAPC assessed as reduction in PDL1 interaction with human PD1 expressed in Jurkat T ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50239947(CHEMBL4089730 | US20230303494, Compound BMS202 | U...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in human Jurkat cells expressing PD-1/NFAT/Luc cocultured with CHO-K1 cells expressing PD-L1/aAPC assessed...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50239947(CHEMBL4089730 | US20230303494, Compound BMS202 | U...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of human PD1 stably expressed in human Jurkat T cells co-expressing NFAT-induced luciferase/human PDL1 stably expressed in CHOK1 cells co-...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547288(CHEMBL4792502)
Affinity DataEC50:  1.22E+4nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM363414((R)-2-((2-((5-cyanopyridin-3-yl)methoxy)-4-((2-met...)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human PDL1 expressed in CHO-K1 cells co-expressing aAPC assessed as reduction in PDL1 interaction with human PD1 expressed in Jurkat T ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547285(CHEMBL4764475)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547287(CHEMBL4752777)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547290(CHEMBL4746303)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547289(CHEMBL4760301)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547286(CHEMBL4757864)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547284(CHEMBL4793935)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50547283(CHEMBL4750124)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of hPD-1/hPD-L1 immune checkpoint using PD-L1 expressing human aAPCs and PD-1 expressing human Jurkat cells assessed as activation of effe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50535767(CHEMBL4473243)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human PDL1 expressed in CHO-K1 cells co-expressing aAPC assessed as reduction in PDL1 interaction with human PD1 expressed in Jurkat T ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed