Compile Data Set for Download or QSAR
maximum 50k data
Found 6 of ki for UniProtKB: P05181
TargetCytochrome P450 2E1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50240850((2-Isothiocyanato-ethyl)-benzene | CHEMBL151649 | ...)
Affinity DataKi:  9.98E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50240850((2-Isothiocyanato-ethyl)-benzene | CHEMBL151649 | ...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human CYP2E1 expressed in Escherichia coli MV1304 assessed as reduction in 7-EFC O-de-ethylation activity by spectrofluorometry based d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50088490(CHEMBL3526979)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate after 5 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363928(CHEMBL1951575)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate after 5 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310823(CHEMBL1078442 | bergamottin)
Affinity DataKi:  4.00E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50088436(BS-749 | CHEBI:76987 | Metacetamol)
Affinity DataKi:  9.50E+6nMAssay Description:Inhibition of human CYP2E1 assessed as chlorzoxazone 6-hydroxylase activity by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed