Compile Data Set for Download or QSAR
maximum 50k data
Found 27 of ki data for polymerid = 5275
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM26621(4-[dihydroxy(oxo)--stibanyl]-2-nitrobenzoic acid |...)
Affinity DataKi:  19nM ΔG°:  -10.4kcal/mole IC50:  4nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM26622(Compound 13793 | ethyl 4-{4-[dihydroxy(oxo)--stiba...)
Affinity DataKi:  36nM ΔG°:  -10.0kcal/mole IC50:  17nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92732(NSC332395, 4)
Affinity DataKi:  120nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318446(NSC332395 | US9624235, Compound 4)
Affinity DataKi:  120nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318443(NSC332398 | US9624235, Compound 1)
Affinity DataKi:  180nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92729(NSC332398, 1)
Affinity DataKi:  180nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92731(NSC332389, 3)
Affinity DataKi:  190nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318445(NSC332389 | US9624235, Compound 3)
Affinity DataKi:  190nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318444(NSC332384 | US9624235, Compound 2)
Affinity DataKi:  220nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92730(NSC332384, 2)
Affinity DataKi:  220nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318448(NSC332397 | US9624235, Compound 6)
Affinity DataKi:  640nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92733(NSC332396, 5)
Affinity DataKi:  680nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318447(NSC332396 | US9624235, Compound 5)
Affinity DataKi:  680nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318454(NSC614430 | US9624235, Compound 13)
Affinity DataKi:  4.90E+3nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92740(NSC614430, 13)
Affinity DataKi:  4.90E+3nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318452(NSC131534 | US9624235, Compound 11)
Affinity DataKi:  6.70E+3nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92738(NSC131534, 11)
Affinity DataKi:  6.70E+3nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318449(NSC300598 | US9624235, Compound 7)
Affinity DataKi:  1.09E+4nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92735(NSC300598, 7)
Affinity DataKi:  1.09E+4nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92736(NSC89640, 9)
Affinity DataKi:  1.30E+4nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318450(NSC89640 | US9624235, Compound 9)
Affinity DataKi:  1.30E+4nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318451(NSC107215 | US9624235, Compound 10)
Affinity DataKi:  1.70E+4nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92737(NSC107215, 10)
Affinity DataKi:  1.70E+4nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92739(NSC375491, 12 | US9624235, Compound 12)
Affinity DataKi:  3.20E+4nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92739(NSC375491, 12 | US9624235, Compound 12)
Affinity DataKi:  3.20E+4nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM92741(NSC402686, 14)
Affinity DataKi:  3.70E+4nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM318455(NSC402686 | US9624235, Compound 14)
Affinity DataKi:  3.70E+4nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
In DepthDetails US Patent