Compile Data Set for Download or QSAR
maximum 50k data
Found 65 of ki data for polymerid = 5886
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <1nMAssay Description:Inhibition of Bcl-w (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50030754(CHEMBL3342332)
Affinity DataKi:  19nMAssay Description:Binding affinity to BCL-W (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50357756(CHEMBL1916194)
Affinity DataKi:  21nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM21434(N-Benylpiperazine derivative, 23j | N-[(4-{[(2R)-4...)
Affinity DataKi:  49nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50357753(CHEMBL1916191)
Affinity DataKi:  55nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50357755(CHEMBL1916193)
Affinity DataKi:  59nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50357752(CHEMBL1916190)
Affinity DataKi:  63nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50357754(CHEMBL1916192)
Affinity DataKi:  170nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)
Affinity DataKi:  245nMAssay Description:Binding affinity to Bcl-w (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)
Affinity DataKi:  245nMAssay Description:Inhibition of BCL-W (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)
Affinity DataKi:  245nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-W expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi:  285nMAssay Description:Inhibition of Bcl-w (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50078160(CHEMBL3417701)
Affinity DataKi: >660nMAssay Description:Inhibition of BCL-W (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of BH3 peptide binding to human recombinant BCL-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50372177(CHEMBL404899)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50013865(CHEMBL3265297)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50013867(CHEMBL3265299)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50013862(CHEMBL3265294)
Affinity DataKi:  1.92E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM31802(Apogossypol | US9115061, Apogossypol)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of Bcl-w (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50013863(CHEMBL3265295)
Affinity DataKi:  2.19E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50372180(CHEMBL270646)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50372178(CHEMBL406312)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50013864(CHEMBL3265296)
Affinity DataKi:  4.41E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50202271(2-[5-(phenyl(4-biphenyl)methylidene)-4-oxo-2-thiox...)
Affinity DataKi:  6.98E+3nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  7.01E+3nMAssay Description:Inhibition of Bcl-w (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)
Affinity DataKi:  8.19E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50251652(Biphenyl-4-carboxylic acid {[4-(adamantan-1-ylamin...)
Affinity DataKi:  9.43E+3nMAssay Description:Inhibition of 5-carboxyfluorescein-labeled Flu-Bak-BH3 peptide binding to Bcl-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50251651(Biphenyl-4-carboxylic acid methyl-[(3-nitro-4-pipe...)
Affinity DataKi:  1.08E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-labeled Flu-Bak-BH3 peptide binding to Bcl-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM34194(3-chloranyl-1-(3,4-dichlorophenyl)-4-(4-methylpipe...)
Affinity DataKi:  1.25E+4nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-W expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50251616(CHEMBL521427 | biphenyl-4-carboxylic acid methyl-[...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-labeled Flu-Bak-BH3 peptide binding to Bcl-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50372176(CHEMBL272974)
Affinity DataKi:  1.37E+4nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataKi:  1.77E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50200960(CHEMBL216089 | ethyl 2-amino-6-(4-tert-butylphenyl...)
Affinity DataKi:  2.03E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50202277((S)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazo...)
Affinity DataKi:  2.15E+4nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50202277((S)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazo...)
Affinity DataKi:  2.15E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50202275(2-[5-(1-phenylbutylidene)-4-oxo-2-thioxothiazolidi...)
Affinity DataKi:  2.41E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50200964(CHEMBL219234 | ethyl 2-amino-6-cyclopentyl-4-(1-cy...)
Affinity DataKi:  3.08E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50202283(2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidi...)
Affinity DataKi:  3.12E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50013839(CHEMBL2030270)
Affinity DataKi:  3.75E+4nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50372173(CHEMBL404644)
Affinity DataKi:  3.92E+4nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50202272(2-[5-(1-phenylbutylidene)-4-oxo-2-thioxothiazolidi...)
Affinity DataKi:  4.11E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50200962(CHEMBL219366 | ethyl 2-amino-6-phenyl-4-(1-cyano-2...)
Affinity DataKi:  4.12E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50202269(2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidi...)
Affinity DataKi:  5.42E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50200963(CHEMBL425792 | ethyl 2-amino-6-n-propyl-4-(1-cyano...)
Affinity DataKi:  5.67E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50202270(2-propenyl 2-[5-(4-bromobenzylidene)-4-oxo-2-thiox...)
Affinity DataKi:  5.68E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50202282(2-[5-(1-phenylethylidene)-4-oxo-2-thioxothiazolidi...)
Affinity DataKi:  5.83E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50024671(CHEMBL2374449)
Affinity DataKi:  5.93E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50202274(2-[5-(diphenylmethylidene)-4-oxo-2-thioxothiazolid...)
Affinity DataKi:  6.19E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50202278(2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidi...)
Affinity DataKi:  8.80E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50372174(CHEMBL256858)
Affinity DataKi:  8.83E+4nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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