Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ki for UniProtKB: P04035
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18372((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethan...)
Affinity DataKi:  0.900nMAssay Description:Inhibitory constant against HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50139181((1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotet...)
Affinity DataKi:  2.60nMAssay Description:Inhibitory constant against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279858((3R,5R)-7-(2-Benzyloxy-4,6-dichloro-phenyl)-3,5-di...)
Affinity DataKi:  3nMAssay Description:The inhibitory activity of the compound against purified recombinant human HMG-CoA reductase was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM22164((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylca...)
Affinity DataKi:  6.20nMAssay Description:Inhibition of HMG-CoA Reductase (unknown origin)More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279859((S)-4-{[2-(2-Benzyloxy-4,6-dichloro-phenyl)-ethyl]...)
Affinity DataKi:  16nMAssay Description:The inhibitory activity of the compound against purified recombinant human HMG-CoA reductase was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50160720(3-hydroxy-3-methylglutaric acid | 3-hydroxy-3-meth...)
Affinity DataKi:  23.5nMAssay Description:Inhibitory constant against HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50321104(CHEMBL1163804 | DFGYVAE)
Affinity DataKi:  51nMAssay Description:Competitive inhibition of HMG-CoA reductase by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50321100(CHEMBL1164546 | GF(4-fluro)PTGG)
Affinity DataKi:  260nMAssay Description:Competitive inhibition of HMG-CoA reductase by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50139181((1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotet...)
Affinity DataKi:  6.80E+4nMAssay Description:Inhibitory constant against HMG-CoA reductase with alpha asaroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18372((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethan...)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibitory constant against HMG-CoA reductase with alpha asaroneMore data for this Ligand-Target Pair