Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ic50 for UniProtKB: A0A140VK97
TargetCyclin-Y/Cyclin-dependent kinase 16(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50528810(CHEMBL4580787)
Affinity DataIC50:  10nMAssay Description:Competitive irreversible inhibition of CDK16/cyclin Y (unknown origin) in presence of Km ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  17.2nMAssay Description:Inhibition of human CDK16/cyclin-Y using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human CDK16/cyclin-Y using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50573929(CHEMBL4848734)
Affinity DataIC50:  56nMAssay Description:Inhibition of human CDK16/cyclin-Y using RB protein as substrate incubated for 2 hrs by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50598717(CHEMBL5193702 | US20230348487, Example LS 6-45)
Affinity DataIC50:  135nMAssay Description:Inhibition of human CDK16/cyclin-Y protein-protein complexMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50466210(CHEMBL4281048)
Affinity DataIC50:  292nMAssay Description:Inhibition of recombinant GST-tagged inactive state of human CDK16 (108 to end residues)/cyclin Y (2 to end residues)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 16(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186184(US9163013, 1)
Affinity DataIC50:  1.50E+3nMT: 2°CAssay Description:Compound 1 was also assayed to determine the IC50 values for three different kinases (PCTAIRE1, DYRK1a, and CDK2) in comparison to Gsk3beta. The ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-Y/Cyclin-dependent kinase 16(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50539904(CHEMBL4647764)
Affinity DataIC50:  3.83E+3nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human N-terminal GST-tagged human CDK16 (107 to end residues)/Cyclin Y (2 to end residues) exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed