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Found 8 of ic50 for UniProtKB: Q9JJX7
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50179250(CHEMBL3813826)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of mouse recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50438863(10-(4-Hydroxyphenyl)-2,4-dioxo-pyrimido[4,5-b]quin...)
Affinity DataIC50: >1.11E+5nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50438865(2,4-Dioxo-10-phenyl-pyrimido[4,5-b]quinoline-8-car...)
Affinity DataIC50: >1.11E+5nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50438882(10-Phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dion...)
Affinity DataIC50: >1.11E+5nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50179183(CHEMBL576840 | NSC-3198)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of mouse recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50179184(CHEMBL264425)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of mouse recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM188529(2,4-Dioxo-10-[3-(1H-tetrazol-5-yl)phenyl]pyrimido[...)
Affinity DataIC50: >1.11E+5nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50438870(8-Chloro-10-(4-hydroxyphenyl)pyrimido[4,5-b]quinol...)
Affinity DataIC50: >1.11E+5nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed