Compile Data Set for Download or QSAR
maximum 50k data
Found 49 of ec50 data for polymerid = 8119
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543473((((6-chloro-5-(2'-hydroxy-[1,1'-biphenyl]-4- yl)-1...)
Affinity DataEC50:  0.550nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543471((((6-chloro-5-(2'-hydroxy-[1,1'-biphenyl]-4- yl)-1...)
Affinity DataEC50:  0.970nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543477(2-((6-chloro-5-(2'-hydroxy-4'-(1H-1,2,4- triazol-1...)
Affinity DataEC50:  1.10nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192505(US9187477, 1)
Affinity DataEC50:  1.20nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543470(2-((6-chloro-5-(2'-hydroxy-[1,1'-biphenyl]-4- yl)-...)
Affinity DataEC50:  1.40nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543472(US11279702, Compound 3 | ethyl hydrogen (((6-chlor...)
Affinity DataEC50:  2.38nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM201005(US9540364, example 15)
Affinity DataEC50:  3nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM201004(US9540364, example 14)
Affinity DataEC50:  4nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM200996(US9540364, example 8)
Affinity DataEC50:  5nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM201001(US9540364, example 13)
Affinity DataEC50:  5nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM201006(US9540364, example 16)
Affinity DataEC50:  6nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192510(US9187477, 6)
Affinity DataEC50:  6nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM200995(US9540364, example 7)
Affinity DataEC50:  8nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM200992(US9540364, example 3)
Affinity DataEC50:  8nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192508(US9187477, 16 | US9187477, 4)
Affinity DataEC50:  12nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192513(US9187477, 9)
Affinity DataEC50:  17nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543476(2-((5-(4'-(1H-1,2,4-triazol-1-yl)-[1,1'- biphenyl]...)
Affinity DataEC50:  20nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM201007(US9540364, example 17)
Affinity DataEC50:  20nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192514(US9187477, 10)
Affinity DataEC50:  26nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192506(US9187477, 2)
Affinity DataEC50:  32nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM200997(US9540364, example 9)
Affinity DataEC50:  33nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM200998(US9540364, example 10)
Affinity DataEC50:  34nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM201008(US9540364, example 18)
Affinity DataEC50:  34nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192515(US9187477, 11)
Affinity DataEC50:  35nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM201011(US9540364, example 21)
Affinity DataEC50:  38nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543475((S)-2-((6-chloro-5-(4-(3-hydroxypyrrolidin- 1-yl)p...)
Affinity DataEC50:  43nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM201010(US9540364, example 20)
Affinity DataEC50:  50nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM201009(US9540364, example 19)
Affinity DataEC50:  67nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM200999(US9540364, example 12)
Affinity DataEC50:  76nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM200993(US9540364, example 4)
Affinity DataEC50:  104nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192507(US9187477, 3)
Affinity DataEC50:  108nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192509(US9187477, 5)
Affinity DataEC50:  119nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192519(US9187477, 15)
Affinity DataEC50:  133nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543469(US11279702, Compound A1)
Affinity DataEC50:  200nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM200994(US9540364, example 5)
Affinity DataEC50:  209nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM200907(US9540364, example 1)
Affinity DataEC50:  216nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192508(US9187477, 16 | US9187477, 4)
Affinity DataEC50:  290nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192512(US9187477, 8)
Affinity DataEC50:  339nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192511(US9187477, 7)
Affinity DataEC50:  468nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192518(US9187477, 14)
Affinity DataEC50:  578nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543474(2-((6-chloro-5-(4'-(3,3-dimethylbutyl)-2'- hydroxy...)
Affinity DataEC50:  1.12E+3nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192516(US9187477, 12)
Affinity DataEC50:  1.31E+3nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM192517(US9187477, 13)
Affinity DataEC50:  2.04E+3nMpH: 7.0Assay Description:Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM50434271(CHEMBL2385951)
Affinity DataEC50:  2.10E+3nMAssay Description:Activation of recombinant AMPK alpha1 (1 to 394) (unknown origin) after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM200991(US9540364, example 2)
Affinity DataEC50:  4.29E+3nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  8.00E+3nMAssay Description:Activation of human recombinant AMPK alpha1 (1 to 394 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL using SAMS peptide after 10 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  8.00E+3nMAssay Description:Activation of human recombinant AMPK alpha1 subunitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  9.00E+3nMAssay Description:Activation of human AMPK alpha1 (1 to 394) expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM50434272(CHEMBL1242297)
Affinity DataEC50:  9.60E+3nMAssay Description:Activation of recombinant AMPK alpha1 (1 to 394) (unknown origin) after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed