TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 20.2nMAssay Description:To measure the direct binding of small molecules with CFTR, the interaction between small molecules and membrane fragments derived from HEK293 cells ...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 700nMAssay Description:Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influxMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 800nMAssay Description:Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influxMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 800nMAssay Description:Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influxMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 900nMAssay Description:Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influxMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 1.10E+3nMAssay Description:Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influxMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 1.10E+3nMAssay Description:Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influxMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 1.10E+3nMAssay Description:Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influxMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 1.10E+3nMAssay Description:Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influxMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 1.10E+3nMAssay Description:Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influxMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 9.66E+3nMAssay Description:To measure the direct binding of small molecules with CFTR, the interaction between small molecules and membrane fragments derived from HEK293 cells ...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 2.56E+4nMAssay Description:Binding affinity to sensorchip-immobilized human His-tagged CFTR F508 deletion mutant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 3.82E+4nMAssay Description:Binding affinity to His-tagged human CFTR-F508del mutant by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 4.78E+4nMAssay Description:Binding affinity to sensorchip-immobilized human His-tagged CFTR F508 deletion mutant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
3D Structure (crystal)TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 6.58E+4nMAssay Description:Binding affinity to sensorchip-immobilized human His-tagged CFTR F508 deletion mutant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 7.28E+4nMAssay Description:Binding affinity to His-tagged human CFTR-F508del mutant by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 8.93E+4nMAssay Description:Binding affinity to His-tagged human CFTR-F508del mutant by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 1.75E+5nMAssay Description:Binding affinity to sensorchip-immobilized human His-tagged CFTR F508 deletion mutant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 1.89E+5nMAssay Description:Binding affinity to sensorchip-immobilized human His-tagged CFTR F508 deletion mutant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
