Affinity DataEC50: 2nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMpH: 7.2 T: 2°CAssay Description:293E cells (EBNA1-expressing IIEK293 cells, ATCC No. CRL-10852) were cultured in DMEM (1.0 g/ml Glucose-containing Dulbecco's modified Eagle medium, ...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMpH: 7.2 T: 2°CAssay Description:293E cells (EBNA1-expressing IIEK293 cells, ATCC No. CRL-10852) were cultured in DMEM (1.0 g/ml Glucose-containing Dulbecco's modified Eagle medium, ...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMpH: 7.2 T: 2°CAssay Description:293E cells (EBNA1-expressing IIEK293 cells, ATCC No. CRL-10852) were cultured in DMEM (1.0 g/ml Glucose-containing Dulbecco's modified Eagle medium, ...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMpH: 7.2 T: 2°CAssay Description:293E cells (EBNA1-expressing IIEK293 cells, ATCC No. CRL-10852) were cultured in DMEM (1.0 g/ml Glucose-containing Dulbecco's modified Eagle medium, ...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Displacement of [3H]CP55940 from mouse brain CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 7.90nMAssay Description:Agonist activity at human beta-2 adrenergic receptor expressed in human H292 cells assessed as accumulation of intracellular cAMP after 1 hr by Alpha...More data for this Ligand-Target Pair
Affinity DataEC50: 7.90nMAssay Description:Displacement of [3H]CP55940 from mouse brain CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Positive allosteric modulation of calcium sensing receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human beta-2 adrenergic receptor expressed in human H292 cells assessed as accumulation of intracellular cAMP after 1 hr by Alpha...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Displacement of [3H]CP55940 from human brain CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at human beta-2 adrenergic receptor expressed in human H292 cells assessed as accumulation of intracellular cAMP after 1 hr by Alpha...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Agonist activity at human CaSR expressed in CHO cells assessed as increase in intracellular calcium mobilization after 1 hr by Fura-2 dye-based fluor...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMpH: 7.2 T: 2°CAssay Description:293E cells (EBNA1-expressing IIEK293 cells, ATCC No. CRL-10852) were cultured in DMEM (1.0 g/ml Glucose-containing Dulbecco's modified Eagle medium, ...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 19.9nMAssay Description:Positive allosteric modulation of calcium sensing receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 25.1nMAssay Description:Positive allosteric modulation of calcium sensing receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: 31.6nMAssay Description:Positive allosteric modulation of calcium sensing receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Agonist activity at human beta-2 adrenergic receptor expressed in human H292 cells assessed as accumulation of intracellular cAMP after 1 hr by Alpha...More data for this Ligand-Target Pair
Affinity DataEC50: 36nMAssay Description:Activation of human CaSRMore data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 39nMpH: 7.2 T: 2°CAssay Description:293E cells (EBNA1-expressing IIEK293 cells, ATCC No. CRL-10852) were cultured in DMEM (1.0 g/ml Glucose-containing Dulbecco's modified Eagle medium, ...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMpH: 7.2 T: 2°CAssay Description:293E cells (EBNA1-expressing IIEK293 cells, ATCC No. CRL-10852) were cultured in DMEM (1.0 g/ml Glucose-containing Dulbecco's modified Eagle medium, ...More data for this Ligand-Target Pair