Compile Data Set for Download or QSAR
maximum 50k data
Found 47 of ec50 for UniProtKB: P17787
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50240856(7-Methyl-2-pyridazin-4-yl-7-aza-bicyclo[2.2.1]hept...)
Affinity DataEC50:  13nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498034(CHEMBL3329543)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498033(CHEMBL3329540)
Affinity DataEC50:  53nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498045(CHEMBL3329537)
Affinity DataEC50:  62nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498051(CHEMBL3329528)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498046(CHEMBL3329538)
Affinity DataEC50:  88nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498052(CHEMBL3329546)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498035(CHEMBL3329530)
Affinity DataEC50:  180nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498041(CHEMBL3329531)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498040(CHEMBL3329533)
Affinity DataEC50:  370nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50530216(CHEMBL4582201)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50530216(CHEMBL4582201)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498053(CHEMBL3329545)
Affinity DataEC50:  540nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498047(CHEMBL3329539)
Affinity DataEC50:  620nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50459884(CHEMBL4228846)
Affinity DataEC50:  660nMAssay Description:Positive allosteric modulation of human alpha2beta2 nAChR expressed in HEK cells preincubated for 15 mins followed by dihydro-beta-erythroidine hydro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50445605(CHEMBL3104001)
Affinity DataEC50:  690nMAssay Description:Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50445612(CHEMBL3103985)
Affinity DataEC50:  700nMAssay Description:Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50498044(CHEMBL3329529)
Affinity DataEC50:  750nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50445611(CHEMBL3103988)
Affinity DataEC50:  790nMAssay Description:Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50498048(CHEMBL3329541)
Affinity DataEC50:  920nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50445610(CHEMBL3104068)
Affinity DataEC50:  1.00E+3nMAssay Description:Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50445609(CHEMBL3103999)
Affinity DataEC50:  1.30E+3nMAssay Description:Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50498049(CHEMBL3329534)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50445608(CHEMBL3104126)
Affinity DataEC50:  1.70E+3nMAssay Description:Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50498037(CHEMBL3329535)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498038(CHEMBL3329542)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50445607(CHEMBL3104079)
Affinity DataEC50:  2.00E+3nMAssay Description:Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/alpha-5/beta-2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50445606(CHEMBL3103983)
Affinity DataEC50:  2.20E+3nMAssay Description:Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50530218(CHEMBL4515416)
Affinity DataEC50:  2.86E+3nMAssay Description:Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50530218(CHEMBL4515416)
Affinity DataEC50:  2.86E+3nMAssay Description:Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50052593(3-Ethynyl-5-((S)-1-methyl-azetidin-2-yl)-pyridine ...)
Affinity DataEC50:  3.20E+3nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50498050(CHEMBL3329544)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50530217(CHEMBL4550498)
Affinity DataEC50:  6.32E+3nMAssay Description:Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50530217(CHEMBL4550498)
Affinity DataEC50:  6.32E+3nMAssay Description:Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50364890(Amixin IC | TILORONE | cid_5475)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha3beta2 nAChR receptor by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50498032(CHEMBL3329532)
Affinity DataEC50:  1.60E+4nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498039(CHEMBL3357969)
Affinity DataEC50:  2.10E+4nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50061567(1,1-Dimethyl-4-phenyl-piperazin-1-ium | CHEMBL1347...)
Affinity DataEC50:  5.60E+4nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50530215(CHEMBL4475133)
Affinity DataEC50:  6.55E+4nMAssay Description:Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50530215(CHEMBL4475133)
Affinity DataEC50:  6.55E+4nMAssay Description:Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50143282((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...)
Affinity DataEC50:  6.70E+4nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170601((1R,10S)-9-oxa-4,13-diazatetracyclo[11.2.1.0^{1,10...)
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170598(5'-phenyl-3'H-4-azaspiro[bicyclo[2.2.2]octane-2,2'...)
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  1.32E+5nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)
Affinity DataEC50:  4.43E+5nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50093255((+)-Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidi...)
Affinity DataEC50: >1.00E+6nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170583(1H-Indole-3-carboxylic acid 1-(1-methyl-pyrrolidin...)
Affinity DataEC50: >1.00E+6nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed