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Found 7 of ic50 for UniProtKB: P04757
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-3(Rattus norvegicus)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445330(CHEMBL3104243)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-3(Rattus norvegicus)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445322(CHEMBL3104235)
Affinity DataIC50:  28nMAssay Description:Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current by voltage clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-3(Rattus norvegicus)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445324(CHEMBL3104237)
Affinity DataIC50:  140nMAssay Description:Antagonist activity at Sprague-Dawley rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-3(Rattus norvegicus)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445331(CHEMBL3104245)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current after 2 to 4 days b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rattus norvegicus (Rat))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241747(3-demethoxy-2alpha,3alpha-methylenedioxyerythrocul...)
Affinity DataIC50:  7.70E+4nMAssay Description:Antagonist activity at rat alpha3beta4 nicotinic receptor expressed in KXalpha3beta4R2 cells assessed as nicotine-induced calcium fluorescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rattus norvegicus (Rat))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241746(15-amido-3-demethoxy-2alpha,3alpha-methylenedioxye...)
Affinity DataIC50:  9.40E+4nMAssay Description:Antagonist activity at rat alpha3beta4 nicotinic receptor expressed in KXalpha3beta4R2 cells assessed as nicotine-induced calcium fluorescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rattus norvegicus (Rat))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241748(CHEMBL518059 | dihydro-beta-erythroidine)
Affinity DataIC50:  1.00E+5nMAssay Description:Activity at rat alpha3beta4 nicotinic receptor expressed in KXalpha3beta4R2 cells assessed as nicotine-induced 86Rb+ effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed