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Compile Data Set for Download or QSAR

Found 8 hits of affinity data for UniProtKB/TrEMBL: P9WGZ1   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA-directed RNA polymerase subunit alpha


()
BDBM466519
PNG
(US10800725, Compound 7)
Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccccc2C)=C1O
Show InChI InChI=1S/C31H46O4/c1-20(2)12-14-25-28(33)27(26(32)15-13-24-11-9-8-10-23(24)7)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h8-11,20-22,33-34H,12-19H2,1-7H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 170n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...


US Patent US10800725 (2020)

More data for this
Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha


()
BDBM466524
PNG
(US10800725, Compound 12)
Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(cc2)C(F)(F)F)=C1O
Show InChI InChI=1S/C31H43F3O4/c1-19(2)7-13-24-27(36)26(25(35)14-10-22-8-11-23(12-9-22)31(32,33)34)29(38)30(28(24)37,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,36-37H,7,10,13-18H2,1-6H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 220n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...


US Patent US10800725 (2020)

More data for this
Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha


()
BDBM466521
PNG
(US10800725, Compound 9)
Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(C)cc2)=C1O
Show InChI InChI=1S/C31H46O4/c1-20(2)8-14-25-28(33)27(26(32)15-13-24-11-9-23(7)10-12-24)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h9-12,20-22,33-34H,8,13-19H2,1-7H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 290n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...


US Patent US10800725 (2020)

More data for this
Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha


()
BDBM466520
PNG
(US10800725, Compound 8)
Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2cccc(C)c2)=C1O
Show InChI InChI=1S/C31H46O4/c1-20(2)11-13-25-28(33)27(26(32)14-12-24-10-8-9-23(7)19-24)30(35)31(29(25)34,17-15-21(3)4)18-16-22(5)6/h8-10,19-22,33-34H,11-18H2,1-7H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 600n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...


US Patent US10800725 (2020)

More data for this
Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha


()
BDBM466522
PNG
(US10800725, Compound 10)
Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(F)cc2)=C1O
Show InChI InChI=1S/C30H43FO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 640n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...


US Patent US10800725 (2020)

More data for this
Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha


()
BDBM466526
PNG
(US10800725, Compound 14)
Show SMILES CCCCC1=C(O)C(CCCC)(CCCC)C(=O)C(C(=O)CCc2ccc(Cl)cc2)=C1O
Show InChI InChI=1S/C27H37ClO4/c1-4-7-10-21-24(30)23(22(29)16-13-19-11-14-20(28)15-12-19)26(32)27(25(21)31,17-8-5-2)18-9-6-3/h11-12,14-15,30-31H,4-10,13,16-18H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 680n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...


US Patent US10800725 (2020)

More data for this
Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha


()
BDBM466515
PNG
(US10800725, Compound 3)
Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(Cl)cc2)=C1O
Show InChI InChI=1S/C30H43ClO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 770n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...


US Patent US10800725 (2020)

More data for this
Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha


()
BDBM466523
PNG
(US10800725, Compound 11)
Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(Br)cc2)=C1O
Show InChI InChI=1S/C30H43BrO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 780n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...


US Patent US10800725 (2020)

More data for this
Ligand-Target Pair