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Compile Data Set for Download or QSAR

Found 2 hits of affinity data for UniProtKB/TrEMBL: P66706   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA-directed RNA polymerase subunit alpha


()
BDBM466524
PNG
(US10800725, Compound 12)
Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(cc2)C(F)(F)F)=C1O
Show InChI InChI=1S/C31H43F3O4/c1-19(2)7-13-24-27(36)26(25(35)14-10-22-8-11-23(12-9-22)31(32,33)34)29(38)30(28(24)37,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,36-37H,7,10,13-18H2,1-6H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 460n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...


US Patent US10800725 (2020)

More data for this
Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha


()
BDBM466521
PNG
(US10800725, Compound 9)
Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(C)cc2)=C1O
Show InChI InChI=1S/C31H46O4/c1-20(2)8-14-25-28(33)27(26(32)15-13-24-11-9-23(7)10-12-24)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h9-12,20-22,33-34H,8,13-19H2,1-7H3
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 840n/an/an/an/an/an/a



TBA

US Patent


Assay Description
Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...


US Patent US10800725 (2020)

More data for this
Ligand-Target Pair