Compile Data Set for Download or QSAR
maximum 50k data
Found 21 of ec50 data for complexid = 50000285
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)
Affinity DataEC50:  0.0530nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50143282((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...)
Affinity DataEC50:  11nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50161090(9-Chloro-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[...)
Affinity DataEC50:  28nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50161085(9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1...)
Affinity DataEC50:  31nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50161083(11,11-dimethyl-6-oxo-7-aza-11-azoniatricyclo[7.3.1...)
Affinity DataEC50:  37nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50161086(9-Iodo-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[1,...)
Affinity DataEC50:  45nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50161089(11-Chloro-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido...)
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50161088(11-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-pyrido[...)
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50161087(9,11-Diiodo-1,2,3,4,5,6-hexahydro-1,5-methano-pyri...)
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50161084(1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,...)
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50161091(9,11-Dibromo-1,2,3,4,5,6-hexahydro-1,5-methano-pyr...)
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50161092(9,11-Dichloro-1,2,3,4,5,6-hexahydro-1,5-methano-py...)
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50210334(CHEMBL3948977)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50210336(CHEMBL3899499)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50210332(CHEMBL3889475)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50210333(CHEMBL3908556)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50210338(CHEMBL3926480)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50210335(CHEMBL3898434)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM86544(CAS_192231-16-6 | CHEMBL111580 | NSC_6442277 | SIB...)
Affinity DataEC50:  5.20E+4nMAssay Description:The compound was tested on recombinant human alpha-1-beta-1-gamma-delta cell lines of human embryonic kidney for nicotinic acetylcholine receptor ago...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM86544(CAS_192231-16-6 | CHEMBL111580 | NSC_6442277 | SIB...)
Affinity DataEC50:  5.30E+4nMAssay Description:Binding affinity at NAChRs was determined by measuring the displacement of ([3H]Nic) from a preparation of rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed