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Found 14 Enz. Inhib. hit(s) with all data for entry = 50034912
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(CHEMBL102521 | N-hydroxyglycine derivative)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(CHEMBL102521 | N-hydroxyglycine derivative)
Affinity DataIC50:  230nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(CHEMBL102521 | N-hydroxyglycine derivative)
Affinity DataIC50:  950nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 1.2 mM NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290880(CHEMBL318550 | [Hydroxy-((2E,6E)-3,7,11-trimethyl-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50059865(4,8,12-trimethyl-(3E,7E)-3,7,11-tridecatrienylhydr...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290883(CHEMBL102874 | N-hydroxyglycine derivative)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290887(CHEMBL99892 | N-hydroxyglycine derivative)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290888(CHEMBL102520 | N-hydroxyglycine derivative)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290881(CHEMBL319416 | N-hydroxyglycine derivative)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290885(CHEMBL99944 | N-hydroxyglycine derivative)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(CHEMBL102521 | N-hydroxyglycine derivative)
Affinity DataIC50:  5.70E+4nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290886(CHEMBL102570 | N-hydroxyglycine derivative)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290879(CHEMBL102600 | [Hydroxy-((2E,6E)-3,7,11-trimethyl-...)
Affinity DataIC50:  5.23E+5nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290884(((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylami...)
Affinity DataIC50:  6.40E+5nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article