Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50044174
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50007728(CHEMBL424121 | DB867)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50210461((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50210461((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...)
Affinity DataIC50:  4.41E+4nMAssay Description:Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50:  1.66E+5nMAssay Description:Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50210461((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...)
Affinity DataIC50:  1.73E+5nMAssay Description:Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50007728(CHEMBL424121 | DB867)
Affinity DataIC50:  1.86E+5nMAssay Description:Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50007728(CHEMBL424121 | DB867)
Affinity DataIC50:  2.11E+5nMAssay Description:Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50:  2.83E+5nMAssay Description:Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50210461((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
The University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50007728(CHEMBL424121 | DB867)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed