Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50042449
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426340(CHEMBL2321943)
Affinity DataKi:  1.70nMAssay Description:Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426341(CHEMBL2321944)
Affinity DataKi:  7.10nMAssay Description:Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386310(CHEMBL2049092)
Affinity DataKi:  7.70nMAssay Description:Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataKi:  14nMAssay Description:Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386310(CHEMBL2049092)
Affinity DataIC50:  22nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataIC50:  23nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426341(CHEMBL2321944)
Affinity DataIC50:  23nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426340(CHEMBL2321943)
Affinity DataIC50:  37nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine--oxoglutarate transaminase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426341(CHEMBL2321944)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of human KAT3 using L-kynurenine as substrate measured after 24 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426341(CHEMBL2321944)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of human KAT1 using L-kynurenine as substrate measured after 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine--oxoglutarate transaminase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386310(CHEMBL2049092)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of human KAT3 using L-kynurenine as substrate measured after 24 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine--oxoglutarate transaminase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataIC50:  9.04E+3nMAssay Description:Inhibition of human KAT3 using L-kynurenine as substrate measured after 24 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine--oxoglutarate transaminase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426340(CHEMBL2321943)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of human KAT3 using L-kynurenine as substrate measured after 24 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386310(CHEMBL2049092)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of human KAT1 using L-kynurenine as substrate measured after 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataIC50:  3.04E+4nMAssay Description:Inhibition of human KAT1 using L-kynurenine as substrate measured after 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426340(CHEMBL2321943)
Affinity DataIC50: >3.60E+4nMAssay Description:Inhibition of human KAT1 using L-kynurenine as substrate measured after 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed