Compile Data Set for Download or QSAR
maximum 50k data
Found 200 of ph data with Target = 'Cholinesterase'
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  36nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29403(tacrine-dihydropyridine hybrid (tacripyrine), 14)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29391(CHEMBL219172 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29392(tacrine-dihydropyridine hybrid (tacripyrine), 3)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29393(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  4.80E+3nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29394(CHEMBL220294 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29395(CHEMBL219405 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  3.44E+4nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29396(CHEMBL219406 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29397(tacrine-dihydropyridine hybrid (tacripyrine), 8)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29398(CHEMBL436302 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29399(CHEMBL218940 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29400(CHEMBL374184 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29401(tacrine-dihydropyridine hybrid (tacripyrine), 12)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29402(tacrine-dihydropyridine hybrid (tacripyrine), 13)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29390(CHEMBL218939 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234351(8-Benzyl-2,3,6,7,8,9-hexahydro-imidazo[1,2-a]pyrid...)
Affinity DataIC50: >2.00E+5nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234352(9-Benzyl-2,3,4,7,8,9,10,12-octahydro-6H-pyrido[4&#...)
Affinity DataIC50:  5.15E+4nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234353(2,3,8,9,10,11-Hexahydro-benzothieno[3,2-e]imidazo[...)
Affinity DataIC50:  8.80E+4nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234354(3,4,9,10,11,12-Hexahydro-2H-benzothieno[3,2-e]pyri...)
Affinity DataIC50:  1.31E+5nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234355(9-Benzyl-2,3,8,9,10,11-hexahydro-imidazo[1,2-c]pyr...)
Affinity DataIC50:  8.99E+4nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234356(10-Benzyl-3,4,9,10,11,12-hexahydro-2H-pyrido[4R...)
Affinity DataIC50:  1.19E+5nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234349(2,3,6,7,8,9-Hexahydro-benzothieno[2,3-d]-imidazo[1...)
Affinity DataIC50: >2.00E+5nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234350(2,3,4,7,8,9,10,12-Octahydro-6H-benzothieno[2,3-d]p...)
Affinity DataIC50: >2.00E+5nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)
Affinity DataIC50:  1.60E+7nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM91730(Carbacylamidophosphate, 4b)
Affinity DataIC50:  1.67E+7nM Kd:  3.36E+7nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234368(K203 (4))
Affinity DataIC50:  3.13E+3nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234370(but-(2E)-en-1,4-diyl-1,1'-bis(4-ethylpyridiniu...)
Affinity DataIC50:  8.50E+5nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM50334312(1,4-bis(4-tert.butylpyridinium)-but-(2E)-ene-1,4-d...)
Affinity DataIC50:  1.69E+5nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234371(but-(2E)-en-1,4-diyl-1,1'-bis(4-phenylpyridini...)
Affinity DataIC50:  1.80E+4nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234372(but-(2E)-en-1,4-diyl-1,1'-bis(4-(3-phenylpropy...)
Affinity DataIC50:  2.20E+4nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234373(but-(2E)-en-1,4-diyl-1,1'-bis(4-(4-nitrobenzyl...)
Affinity DataIC50:  1.80E+4nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234375(but-(2E)-en-1,4-diyl-1,1'-bis(4-hydroxymethylp...)
Affinity DataIC50:  4.51E+6nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234376(but-(2E)-en-1,4-diyl-1,1'-bis(4-(3-hydroxyprop...)
Affinity DataIC50:  1.44E+6nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234377(but-(2E)-en-1,4-diyl-1,1'-bis(4-(N,N-dimethyla...)
Affinity DataIC50:  1.70E+4nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234378(but-(2E)-en-1,4-diyl-1,1'-bis(4-hydroxyiminome...)
Affinity DataIC50:  1.62E+6nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234379(but-(2E)-en-1,4-diyl-1,1'-bis(4-methylcarbonyl...)
Affinity DataIC50:  3.24E+5nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM234383(but-(2E)-en-1,4-diyl-1,1'-bis(4-carbonitrilpyr...)
Affinity DataIC50:  5.14E+5nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM50259982(CHEMBL471187 | US10106521, Compound Eckol | eckol)
Affinity DataIC50:  3.32E+4nMpH: 7.4 T: 2°CAssay Description:Enzyme activities were determined at room temperature. Ultraviolet absorbance was measured spectrophotometrically by a modification of a previously d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM293398(US10106521, Compound 9-O-Methyl Eckol)
Affinity DataIC50:  1.01E+4nMpH: 7.4 T: 2°CAssay Description:Enzyme activities were determined at room temperature. Ultraviolet absorbance was measured spectrophotometrically by a modification of a previously d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM293399(US10106521, Compound 9-O-Benzyl Eckol)
Affinity DataIC50:  8.60E+3nMpH: 7.4 T: 2°CAssay Description:Enzyme activities were determined at room temperature. Ultraviolet absorbance was measured spectrophotometrically by a modification of a previously d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM50259983(CHEMBL508791 | US10106521, Compound Dieckol | diec...)
Affinity DataIC50:  2.50E+3nMpH: 7.4 T: 2°CAssay Description:Enzyme activities were determined at room temperature. Ultraviolet absorbance was measured spectrophotometrically by a modification of a previously d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM293401(US10106521, Compound 9''-O-Methyl Dieckol)
Affinity DataIC50:  1.40E+3nMpH: 7.4 T: 2°CAssay Description:Enzyme activities were determined at room temperature. Ultraviolet absorbance was measured spectrophotometrically by a modification of a previously d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM293402(US10106521, Compound 9''-O-Benzyl Dieckol)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:Enzyme activities were determined at room temperature. Ultraviolet absorbance was measured spectrophotometrically by a modification of a previously d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM50276756(4,9-bis(3,5-dihydroxyphenoxy)benzofuro[3,2-a]diben...)
Affinity DataIC50:  1.00E+3nMpH: 7.4 T: 2°CAssay Description:Enzyme activities were determined at room temperature. Ultraviolet absorbance was measured spectrophotometrically by a modification of a previously d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM293404(US10106521, Compound 14-O-Methyl Phlorofucofuroeck...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:Enzyme activities were determined at room temperature. Ultraviolet absorbance was measured spectrophotometrically by a modification of a previously d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM293405(US10106521, Compound 14-O-Benzyl Phlorofucofuroeck...)
Affinity DataIC50:  2.50E+3nMpH: 7.4 T: 2°CAssay Description:Enzyme activities were determined at room temperature. Ultraviolet absorbance was measured spectrophotometrically by a modification of a previously d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM91723(Carbacylamidophosphate, 1a)
Affinity DataIC50:  9.20E+5nM Kd:  4.30E+7nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM91725(Carbacylamidophosphate, 2a)
Affinity DataIC50:  6.50E+5nM Kd:  2.10E+6nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM91727(Carbacylamidophosphate, 3a)
Affinity DataIC50:  4.80E+6nM Kd:  1.80E+7nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM91729(Carbacylamidophosphate, 4a)
Affinity DataIC50:  1.20E+6nM Kd:  8.90E+6nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 200 total ) | Next | Last >>
Jump to: