TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 11nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 16nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 19nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 80nM ΔG°: -40.1kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 100nM ΔG°: -39.6kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 100nM ΔG°: -39.6kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 100nM ΔG°: -39.6kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 200nM ΔG°: -37.9kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 200nM ΔG°: -37.9kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 200nM ΔG°: -37.9kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 200nM ΔG°: -37.9kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 300nM ΔG°: -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 300nM ΔG°: -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 300nM ΔG°: -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 300nM ΔG°: -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 300nM ΔG°: -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 488nM ΔG°: -35.7kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 500nM ΔG°: -35.6kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 500nM ΔG°: -35.6kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 817nM ΔG°: -34.4kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.30E+3nM ΔG°: -33.3kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.60E+3nM ΔG°: -32.7kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.60E+3nM ΔG°: -32.7kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.80E+3nM ΔG°: -32.5kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 2.20E+3nM ΔG°: -32.0kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 2.71E+3nM ΔG°: -31.5kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 2.74E+3nM ΔG°: -31.4kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
Affinity DataKi: 2.83E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional
receptor assays are available on the NIMH PDSP website at
http://pdsp.med.un...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 3.00E+3nM ΔG°: -31.2kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 3.10E+3nM ΔG°: -31.1kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 5.46E+3nM ΔG°: -29.7kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
Affinity DataKi: 6.65E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional
receptor assays are available on the NIMH PDSP website at
http://pdsp.med.un...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 6.81E+3nM ΔG°: -29.2kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 7.21E+3nM ΔG°: -29.1kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 7.77E+3nM ΔG°: -28.9kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
Affinity DataKi: 8.29E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional
receptor assays are available on the NIMH PDSP website at
http://pdsp.med.un...More data for this Ligand-Target Pair
Affinity DataKi: 8.36E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional
receptor assays are available on the NIMH PDSP website at
http://pdsp.med.un...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 8.67E+3nM ΔG°: -28.6kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 8.74E+3nM ΔG°: -28.6kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 8.89E+3nM ΔG°: -28.5kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 9.28E+3nM ΔG°: -28.4kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 9.31E+3nM ΔG°: -28.4kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 9.46E+3nM ΔG°: -28.4kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 9.58E+3nM ΔG°: -28.4kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 9.83E+3nM ΔG°: -28.3kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.00E+4nM ΔG°: -28.3kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.00E+4nM ΔG°: -28.3kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.00E+4nM ΔG°: -28.3kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
US Patent
University Of North Carolina At Chapel Hill
US Patent
Affinity DataKi: 1.00E+4nM ΔG°: -28.3kJ/molepH: 7.4 T: 2°CAssay Description:Affinities for D3-dopaminergic, D2-dopaminergic and beta2-adrenergic receptors were determined by radioligand competition binding at the National Ins...More data for this Ligand-Target Pair