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Found 25 of ph data with Target = 'Legumain'
TargetLegumain(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM228617(US9345789, LI-0)
Affinity DataIC50:  11.5nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLegumain(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM228617(US9345789, LI-0)
Affinity DataIC50:  704nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLegumain(Mus musculus)
Stanford University

LigandPNGBDBM36333(LI-0 | Legumain Inhibitor -0)
Affinity DataIC50:  704nMpH: 5.8 T: 2°CAssay Description:IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Mus musculus)
Stanford University

LigandPNGBDBM36332(LI-1 | Legumain Inhibitor -1)
Affinity DataIC50:  11.5nMpH: 5.8 T: 2°CAssay Description:IC50 measurements and enzyme kinetics assays were performed on a Spectramax M5 fluorescent plate reader (Molecular Devices).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
The Board Of Trustees Of The Leland Stanford Junior University

US Patent
LigandPNGBDBM228617(US9345789, LI-0)
Affinity DataIC50:  145nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22121(aza-peptide Michael acceptor, 5e | benzyl N-[(1S)-...)
Affinity DataIC50:  1.00E+3nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22122(aza-peptide Michael acceptor, 5f | benzyl N-[(1S)-...)
Affinity DataIC50:  800nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22123(aza-peptide Michael acceptor, 5g | benzyl N-[(1S)-...)
Affinity DataIC50:  600nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22124(aza-peptide Michael acceptor, 5h | benzyl N-[(1S)-...)
Affinity DataIC50:  60nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22125(aza-peptide Michael acceptor, 5i | benzyl N-[(1S)-...)
Affinity DataIC50:  55nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22126(aza-peptide Michael acceptor, 5j | benzyl N-[(1S)-...)
Affinity DataIC50:  35nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22127(aza-peptide Michael acceptor, 5k | benzyl N-[(1S)-...)
Affinity DataIC50:  600nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22128(aza-peptide Michael acceptor, 5l | benzyl N-[(1S)-...)
Affinity DataIC50:  70nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22129(aza-peptide Michael acceptor, 5m | benzyl N-[(1S)-...)
Affinity DataIC50:  45nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22130(aza-peptide Michael acceptor, 5n | benzyl N-[(1S)-...)
Affinity DataIC50:  90nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22131(aza-peptide Michael acceptor, 7c | benzyl N-[(1S)-...)
Affinity DatapH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22132(aza-peptide Michael acceptor, 7d | benzyl N-[(1S)-...)
Affinity DatapH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22133(aza-peptide Michael acceptor, 7e | benzyl N-[(1S)-...)
Affinity DataIC50: >2.00E+3nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22134(aza-peptide Michael acceptor, 7f | benzyl N-[(1S)-...)
Affinity DataIC50: >2.00E+3nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22120(aza-peptide Michael acceptor, 5d | benzyl N-[(1S)-...)
Affinity DataIC50:  700nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22119(aza-peptide Michael acceptor, 5c | benzyl N-[(1S)-...)
Affinity DataIC50:  1.00E+3nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22118(aza-peptide Michael acceptor, 5b | benzyl N-[(1S)-...)
Affinity DataIC50:  550nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22117(aza-peptide Michael acceptor, 5a | benzyl N-[(1S)-...)
Affinity DatapH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22114(aza-peptide Michael acceptor, 7a | ethyl (2E)-4-[(...)
Affinity DataIC50:  31nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Schistosoma mansoni)
Georgia Institute Of Technology

LigandPNGBDBM22116(aza-peptide Michael acceptor, 7b | benzyl (2E)-3-{...)
Affinity DataIC50:  38nMpH: 6.8 T: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed