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Found 23 of ph data with Target = 'Lysosomal alpha-glucosidase'
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataEC50:  9.88E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)
Affinity DataEC50:  7.45E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM50259956(2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)
Affinity DataEC50:  2.81E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM18364((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-nonylpiperidi...)
Affinity DataEC50:  7.00E+3nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190540(US9181184, 27)
Affinity DataEC50:  1.73E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190539(US9181184, 26)
Affinity DataEC50:  6.60E+3nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataEC50:  1.18E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190528(US9181184, 11)
Affinity DataEC50:  4.77E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190529(US9181184, 15)
Affinity DataEC50:  5.84E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190530(US9181184, 16)
Affinity DataEC50:  6.97E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190531(US9181184, 17 | US9181184, 18)
Affinity DataEC50:  6.53E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190531(US9181184, 17 | US9181184, 18)
Affinity DataEC50:  1.04E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190533(US9181184, 19)
Affinity DataEC50:  3.72E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190534(US9181184, 20)
Affinity DataEC50:  4.68E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190535(US9181184, 21)
Affinity DataEC50:  2.10E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190536(US9181184, 23)
Affinity DataEC50:  1.21E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190537(US9181184, 24)
Affinity DataEC50:  7.71E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM190538(US9181184, 25)
Affinity DataEC50:  6.65E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50076963((3R,5R)-2-Hydroxymethyl-1-methyl-piperidine-3,4,5-...)
Affinity DataKi:  3.69E+5nMpH: 6.5Assay Description:Inhibitory potency for brewer's yeast alpha-glucosidase in 0.01 mM EDTA, 0.01 mM PIPES and 0.2 M NaOAc at pH 6.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50076963((3R,5R)-2-Hydroxymethyl-1-methyl-piperidine-3,4,5-...)
Affinity DataKi:  5.40E+4nMpH: 6.55Assay Description:Inhibitory potency for brewer's yeast alpha-glucosidase in 0.1 M sodium phosphate buffer at pH 6.55.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM243075(α-Gl inhibitor, C3)
Affinity DataKi:  2.50E+3nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25°C with minor changes, according to the meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50:  1.36E+4nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25°C with minor changes, according to the meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
Amicus Therapeutics

US Patent
LigandPNGBDBM243075(α-Gl inhibitor, C3)
Affinity DataIC50:  6.41E+4nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25°C with minor changes, according to the meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed