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Found 59 of ph data with Target = 'Plasminogen'
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50009926(CHEMBL3250026)
Affinity DataKi:  1.20E+6nMpH: 6.0Assay Description:Competitive inhibition of 4.8 X 10'-7 M human plasmin using Z-Lys-nitrophenyl ester as substrate incubated up to 1 hr at pH 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)
Affinity DataKi:  8.20nMpH: 7.4Assay Description:Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14350(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-1,3-benz...)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.7kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14481(CA-23 | [amino({5-[(3,4-dihydroxynaphthalene-2-)am...)
Affinity DataKi:  4.00E+3nM ΔG°:  -30.5kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM240790(H-D-Ser-Phg-Arg-OH (1))
Affinity DataKi:  5.70E+3nMpH: 7.4Assay Description:Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM240792(H-D-Ser-homoPhe-Arg-OH (3))
Affinity DataKi:  5.90E+3nMpH: 7.4Assay Description:Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14333(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-1,3-benz...)
Affinity DataKi:  6.40E+3nM ΔG°:  -29.3kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM240793(H-D-Ser-Chg-Arg-OH (4))
Affinity DataKi:  7.70E+3nMpH: 7.4Assay Description:Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM240797(H-D-Ser-1ACH-Arg-OH (8))
Affinity DataKi:  7.70E+3nMpH: 7.4Assay Description:Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM240796(H-D-Ser-αMePhe-Arg-OH (7))
Affinity DataKi:  7.90E+3nMpH: 7.4Assay Description:Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM240791(H-D-Ser-Phe-Arg-OH (2))
Affinity DataKi:  8.70E+3nMpH: 7.4Assay Description:Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM240794(H-D-Ser-Cha-Arg-OH (5))
Affinity DataKi:  8.90E+3nMpH: 7.4Assay Description:Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM240795(H-D-Ser-homoCha-Arg-OH (6))
Affinity DataKi:  1.12E+4nMpH: 7.4Assay Description:Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM233005(H-D-Ser-Ala-Arg-NH-(CH2)5-NH2 (4))
Affinity DataKi:  3.70E+4nMpH: 7.4Assay Description:Determination of amidolytic activity was performed as described previously [Okada et al., Chem. Pharm. Bull., 36:1289-1297]. Detailed description of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14483(2-amino-5-[(2-hydroxy-3-phenylbenzene)amido]-1H-1,...)
Affinity DataKi: >7.50E+4nM ΔG°: >-23.3kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14482(2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-...)
Affinity DataKi: >7.50E+4nM ΔG°: >-23.3kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM233009(H-D-Ser-Ala-Arg-NH-(CH2)9-NH2 (8))
Affinity DataKi:  9.00E+4nMpH: 7.4Assay Description:Determination of amidolytic activity was performed as described previously [Okada et al., Chem. Pharm. Bull., 36:1289-1297]. Detailed description of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14480(CA-22 | [amino({4-[(3-hydroxynaphthalene-2-)amido]...)
Affinity DataKi:  1.30E+5nM ΔG°:  -22.0kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14479(CA-21 | [amino({5-[(3-hydroxynaphthalene-2-)amido]...)
Affinity DataKi:  1.30E+5nM ΔG°:  -22.0kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM233006(H-D-Ser-Ala-Arg-NH-(CH2)6-NH2 (5))
Affinity DataKi:  1.81E+5nMpH: 7.4Assay Description:Determination of amidolytic activity was performed as described previously [Okada et al., Chem. Pharm. Bull., 36:1289-1297]. Detailed description of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM233007(H-D-Ser-Ala-Arg-NH-(CH2)7-NH2 (6))
Affinity DataKi:  3.64E+5nMpH: 7.4Assay Description:Determination of amidolytic activity was performed as described previously [Okada et al., Chem. Pharm. Bull., 36:1289-1297]. Detailed description of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM233012(H-D-Ser-Ala-Arg-NH-(CH2)4-OH (11))
Affinity DataKi:  5.45E+5nMpH: 7.4Assay Description:Determination of amidolytic activity was performed as described previously [Okada et al., Chem. Pharm. Bull., 36:1289-1297]. Detailed description of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM233010(H-D-Ser-Ala-Arg-NH-(CH2)2-OH (9))
Affinity DataKi:  7.27E+5nMpH: 7.4Assay Description:Determination of amidolytic activity was performed as described previously [Okada et al., Chem. Pharm. Bull., 36:1289-1297]. Detailed description of ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM233011(H-D-Ser-Ala-Arg-NH-(CH2)3-OH (10))
Affinity DataKi:  1.09E+6nMpH: 7.4Assay Description:Determination of amidolytic activity was performed as described previously [Okada et al., Chem. Pharm. Bull., 36:1289-1297]. Detailed description of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  3.00E+4nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289377(4-{3-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-phe...)
Affinity DataKi:  3.40E+4nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50038002(Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...)
Affinity DataKi:  3.50E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289379(CHEMBL23243 | Pyridin-4-yl-(2-m-tolyloxy-ethyl)-am...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289378(2-(Naphthalene-2-sulfonylamino)-N-[(S)-1-(piperidi...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289380(2-(Pyridin-4-ylamino)-ethanol | CHEMBL24479)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289373(2-(4-Chloro-benzenesulfonylamino)-N-[(R)-1-(piperi...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289375(2-Benzenesulfonylamino-N-[(R)-1-(piperidine-1-carb...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289374((2-Phenoxy-ethyl)-pyridin-4-yl-amine | CHEMBL28531...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50126700(4-Chloro-N-{3-[2-(pyridin-4-ylamino)-ethoxy]-pheny...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070632(4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070596(CHEMBL282549 | N-Methyl-N-{3-[2-(pyridin-4-ylamino...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289376(2-(Naphthalene-2-sulfonylamino)-N-[(R)-1-(piperidi...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289382(4-Chloro-N-(2-{3-[2-(pyridin-4-ylamino)-ethoxy]-ph...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289381(CHEMBL23246 | Naphthalene-2-sulfonic acid {3-[2-(p...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM10458(4-AP | 4-Aminopyridine 10 | CHEMBL284348 | DALFAMP...)
Affinity DataKi: >2.00E+6nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM141387(US8921319, 3)
Affinity DataKi:  0.550nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM141391(US8921319, 15)
Affinity DataKi:  0.680nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380617(CHEMBL2016873)
Affinity DataKi:  0.770nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380623(CHEMBL2016870)
Affinity DataKi:  1.10nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380625(CHEMBL2016872)
Affinity DataKi:  1.90nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380626(CHEMBL2016874)
Affinity DataKi:  2.20nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM141389(US8921319, 10)
Affinity DataKi:  2.5nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380616(CHEMBL2016869)
Affinity DataKi:  4.90nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM141392(US8921319, 14)
Affinity DataKi:  5.40nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
In DepthDetails US Patent
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