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Found 30 of ph data with Target = 'Thyrotropin-releasing hormone receptor'
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173826(1-[(S)-2-Amino-3-(3-methyl-3H-imidazol-4-yl)-propi...)
Affinity DataKi:  3nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)
Affinity DataKi:  10nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)
Affinity DataKi:  20nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173828(1-[2-[5-oxo-(2S)-tetrahydro-1H-2-pyrrolylcarboxami...)
Affinity DataKi:  320nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173828(1-[2-[5-oxo-(2S)-tetrahydro-1H-2-pyrrolylcarboxami...)
Affinity DataKi:  1.70E+4nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173822(1-[3-(2-cyclohexyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-...)
Affinity DataKi: >1.00E+5nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173825(1-[3-(2-isopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-t...)
Affinity DataKi: >1.00E+5nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173821(1-[3-[2-(tert-butyl)-1H-4-imidazolyl]-2-[5-oxo-(2S...)
Affinity DataKi: >1.00E+5nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173822(1-[3-(2-cyclohexyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-...)
Affinity DataKi: >1.00E+5nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173827(1-[3-(2-cyclopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)...)
Affinity DataKi: >1.00E+5nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173825(1-[3-(2-isopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-t...)
Affinity DataKi: >1.00E+5nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173827(1-[3-(2-cyclopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)...)
Affinity DataKi: >1.00E+5nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173824(1-[3-{2-[1-(1-adamantyl)ethyl]-1H-4-imidazolyl}-2-...)
Affinity DataKi: >1.00E+5nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173821(1-[3-[2-(tert-butyl)-1H-4-imidazolyl]-2-[5-oxo-(2S...)
Affinity DataKi: >1.00E+5nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173824(1-[3-{2-[1-(1-adamantyl)ethyl]-1H-4-imidazolyl}-2-...)
Affinity DataKi: >1.00E+5nMpH: 7.4Assay Description:Inhibitory constant against thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells upon incubation at 37 degee C for 1 hr at pH 7.4 us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173825(1-[3-(2-isopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-t...)
Affinity DataEC50:  1.50E+3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173827(1-[3-(2-cyclopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173822(1-[3-(2-cyclohexyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)
Affinity DataEC50:  3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173824(1-[3-{2-[1-(1-adamantyl)ethyl]-1H-4-imidazolyl}-2-...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173824(1-[3-{2-[1-(1-adamantyl)ethyl]-1H-4-imidazolyl}-2-...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173826(1-[(S)-2-Amino-3-(3-methyl-3H-imidazol-4-yl)-propi...)
Affinity DataEC50:  0.5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173822(1-[3-(2-cyclohexyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-...)
Affinity DataEC50:  1.10E+3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173827(1-[3-(2-cyclopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)...)
Affinity DataEC50:  410nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173821(1-[3-[2-(tert-butyl)-1H-4-imidazolyl]-2-[5-oxo-(2S...)
Affinity DataEC50:  1.30E+3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173828(1-[2-[5-oxo-(2S)-tetrahydro-1H-2-pyrrolylcarboxami...)
Affinity DataEC50:  24nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173828(1-[2-[5-oxo-(2S)-tetrahydro-1H-2-pyrrolylcarboxami...)
Affinity DataEC50:  290nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173821(1-[3-[2-(tert-butyl)-1H-4-imidazolyl]-2-[5-oxo-(2S...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50173825(1-[3-(2-isopropyl-1H-4-imidazolyl)-2-[5-oxo-(2S)-t...)
Affinity DataEC50: >1.00E+5nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)
Affinity DataEC50:  3nMpH: 7.8Assay Description:Signaling (activation) potency for thyrotropin releasing hormone receptor 1 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed