TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 3.57E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.17E+4nM ΔG°: -28.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.17E+4nM ΔG°: -28.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.23E+4nM ΔG°: -28.0kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.29E+4nM ΔG°: -27.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.62E+4nM ΔG°: -27.3kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.81E+4nM ΔG°: -27.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 2.28E+4nM ΔG°: -26.5kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 2.56E+4nM ΔG°: -26.2kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 2.87E+4nM ΔG°: -25.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 3.23E+4nM ΔG°: -25.6kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 5.45E+4nM ΔG°: -24.3kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 9.08E+4nM ΔG°: -23.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.03E+5nM ΔG°: -22.8kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 3.88E+5nM ΔG°: -19.5kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 4.74E+5nM ΔG°: -19.0kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 5.48E+5nM ΔG°: -18.6kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataKi: 1.09E+6nM ΔG°: -16.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 8.60E+4nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 1.20E+4nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 9.30E+3nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 2.12E+5nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 8.00E+3nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 9.10E+3nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 1.04E+4nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 7.80E+3nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 1.10E+3nMpH: 7.0 T: 2°CAssay Description:Assays with and without inhibitor were performed in Corning 96-well clear bottom plates having a nonbinding surface, with a total assay volume of 200...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 5.50E+3nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 5.40E+3nMpH: 7.0Assay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: >1.00E+4nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 65nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 65nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 68nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 75nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 93nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 102nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
East China University Of Science And Technology
Affinity DataIC50: 93nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair