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Found 70 of ph data with Target = 'Tyrosine-protein phosphatase non-receptor type 11'
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM50208877(2-amino-6-chloropurine | 6-Cl-purine (1) | 6-chlor...)
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125938(6-Methoxy-N,9-bis[ (1-{[(2R,3S,4S,5R,6S)-3,4,5-tri...)
Affinity DataIC50:  3.57E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125937(6-Methoxy-N,9-bis[(1-{[(2R,3R,4S,5R,6S)-3,4,5-tris...)
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125936(6-Chloro-N,9-bis[(1-{[(2R,3S,4S,5R,6S)-3,4,5-tris(...)
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125935(6-Chloro-N,9-bis[(1-{[(2R,3R,4S,5R,6S)-3,4,5-tris(...)
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125934(Methyl 6-{4-[(2-Amino-6-methoxy-9H-purin-9-yl)meth...)
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125933(Methyl 6-{4-[(2-Amino-6-methoxy-9H-purin-9-yl)meth...)
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125932(Methyl 6-{4-[(2-Amino-6-chloro-9H-purin-9-yl)methy...)
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125931(Methyl 6-{4-[(2-Amino-6-chloro-9H-purin-9-yl)methy...)
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125930(6-Chloro-9-{[1-(2,3,4,6-tetra-O-acetyl-b-d-glucopy...)
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125929(2-Amino-6-chloro-9-{[1-(2,3,4,6-tetra-O-acetyl-b-d...)
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125928(6-Chloro-N,9-di(prop-2-yn-1-yl)-9H-purin-2-amine (...)
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM125927(6-Chloro-9-(prop-2-yn-1-yl)-9H-purin-2-amine (2))
Affinity DataIC50: >8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 無) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24516((2E,5E)-5-[(4-methoxyphenyl)methylidene]-2-(1,3-th...)
Affinity DataKi:  1.17E+4nM ΔG°:  -28.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24524((2E,5E)-2-(1,3-benzothiazol-2-ylimino)-5-[(4-metho...)
Affinity DataKi:  1.17E+4nM ΔG°:  -28.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24523((2E,5E)-2-{[4-(adamantan-1-yl)-1,3-thiazol-2-yl]im...)
Affinity DataKi:  1.23E+4nM ΔG°:  -28.0kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24526((2E,5E)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylid...)
Affinity DataKi:  1.29E+4nM ΔG°:  -27.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24527((2E,5E)-2-(1,3-benzothiazol-2-ylimino)-5-[(4-nitro...)
Affinity DataKi:  1.62E+4nM ΔG°:  -27.3kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24525((2E,5E)-2-(1,3-benzothiazol-2-ylimino)-5-[(4-hydro...)
Affinity DataKi:  1.81E+4nM ΔG°:  -27.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24529((2Z,5E)-2-(1,2-benzothiazol-3-ylimino)-5-[(4-metho...)
Affinity DataKi:  2.28E+4nM ΔG°:  -26.5kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24515((2E,5E)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]...)
Affinity DataKi:  2.56E+4nM ΔG°:  -26.2kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24528((2E,5E)-2-(1,3-benzothiazol-2-ylimino)-5-[(3-nitro...)
Affinity DataKi:  2.87E+4nM ΔG°:  -25.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24521((2E,5E)-5-[(2-chlorophenyl)methylidene]-2-(1,3-thi...)
Affinity DataKi:  3.23E+4nM ΔG°:  -25.6kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24519((2E,5E)-5-[(4-chlorophenyl)methylidene]-2-(1,3-thi...)
Affinity DataKi:  5.45E+4nM ΔG°:  -24.3kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24530((2Z,5E)-2-(1,2-benzothiazol-3-ylimino)-5-[(4-hydro...)
Affinity DataKi:  9.08E+4nM ΔG°:  -23.1kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24522((2E,5E)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]...)
Affinity DataKi:  1.03E+5nM ΔG°:  -22.8kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24513((2E,5E)-5-[(4-hydroxyphenyl)methylidene]-2-(1,3-th...)
Affinity DataKi:  3.88E+5nM ΔG°:  -19.5kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24517((2E,5E)-5-[(4-nitrophenyl)methylidene]-2-(1,3-thia...)
Affinity DataKi:  4.74E+5nM ΔG°:  -19.0kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24518((2E,5E)-5-[(3-nitrophenyl)methylidene]-2-(1,3-thia...)
Affinity DataKi:  5.48E+5nM ΔG°:  -18.6kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM24520((2E,5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thi...)
Affinity DataKi:  1.09E+6nM ΔG°:  -16.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM50308166(6-hydroxy-1-methyl-3-(1-(3-oxo-3-(phenylamino)prop...)
Affinity DataIC50:  8.60E+4nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM50308165(3-(1-(4-(biphenyl-4-ylamino)-4-oxobutyl)-1H-1,2,3-...)
Affinity DataIC50:  1.20E+4nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM50308164(3-(1-(2-(biphenyl-4-ylamino)-2-oxoethyl)-1H-1,2,3-...)
Affinity DataIC50:  9.30E+3nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM50308163(3-Ethynyl-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-...)
Affinity DataIC50:  2.12E+5nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM50308162(6-hydroxy-1-methyl-3-(1-(5-oxo-5-(10H-phenothiazin...)
Affinity DataIC50:  8.00E+3nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM50308161(3-(1-(2-(benzo[d]thiazol-2-ylamino)-2-oxoethyl)-1H...)
Affinity DataIC50:  9.10E+3nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM50308160(3-(1-(2-(9H-fluoren-9-ylamino)-2-oxoethyl)-1H-1,2,...)
Affinity DataIC50:  1.04E+4nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM50308159(6-hydroxy-1-methyl-3-(1-(2-(4-morpholinophenylamin...)
Affinity DataIC50:  7.80E+3nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM231697(RR601)
Affinity DataIC50:  1.10E+3nMpH: 7.0 T: 2°CAssay Description:Assays with and without inhibitor were performed in Corning 96-well clear bottom plates having a nonbinding surface, with a total assay volume of 200...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM50308158(3-(1-(3-(Biphenyl-4-ylamino)-3-oxopropyl)-1H-1,2,3...)
Affinity DataIC50:  5.50E+3nMpH: 7.0Assay Description:Inhibition of SHP2 Src homology-2 domain expressed in Escherichia coli BL21 (DE3) assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50:  5.40E+3nMpH: 7.0Assay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM231167(US9340574, 7)
Affinity DataIC50: >1.00E+4nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM38042(US10093646, Example 12 | US10774065, Example 12 | ...)
Affinity DataIC50:  65nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM38045(US10093646, Example 13 | US10774065, Example 13 | ...)
Affinity DataIC50:  65nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM38048(US10093646, Example 14 | US10774065, Example 14 | ...)
Affinity DataIC50:  68nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM38067(US10093646, Example 15 | US10774065, Example 15 | ...)
Affinity DataIC50:  75nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM38069(US10093646, Example 16)
Affinity DataIC50:  93nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM38072(US10093646, Example 17 | US10774065, Example 17 | ...)
Affinity DataIC50:  102nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology

LigandPNGBDBM38073(US10093646, Example 18 | US10774065, Example 18 | ...)
Affinity DataIC50:  93nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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